Complex Abdominal Wall Repair Using a Porcine Dermal Matrix

Abstract

Management of complex abdominal defects remains a significant challenge for many surgeons, especially in contaminated fields. Currently, available biosynthetic grafts include human cadaveric dermis (AlloDerm), porcine dermal (Permacol and Strattice), and submucosal (Surgisis) sources. All these grafts are composed of an acellular collagen scaffold to provide a bridge for tissue incorporation and neovascularization. The authors describe a case report of a woman who required dual mesh explantation and successive reparative surgery using a porcine dermal matrix for a complex and infected abdominal wound. Twelve months postdischarge the patient remains well, she is pain free, and she returned home to full activities with complete wound closure and without any evidence of residual or recurrent hernia. The patient was satisfied with her cosmetic results. In conclusion, the authors' experience shows that the use of Permacol, a porcine dermal matrix, has been successful in treating an infected abdomen and a vast abdominal wall defect.

The use of an acellular porcine dermal collagen implant in the repair of complex abdominal wall defects: a European multicentre retrospective study

“…Consequently, the reconstruction of CAWD, termed a complex abdominal wall repair (CAWR), often poses considerable technical challenges. A wide array of techniques has been described in order to achieve repair, including different forms of abdominal wall component separation (with and without prosthetic support), progressive preoperative pneumoperitoneum, and reductive bowel resection [4][5][6][7][8][9][10].…”

Development of a novel approach to safely couple the intestine to a distraction-induced device for intestinal growth: use of reconstructive tissue matrix

“…Grafts composed of acellular collagen provide a scaffold for tissue incorporation[26]. The grafts fused to the serosa of the small bowel.…”

Permacol in Eyelid Reconstruction — A Novel Use

“…It has been used with good clinical results for the treatment of pelvic organ prolapse, 2,3 female urinary stress incontinence, 4 inguinal hernia repair (as an alternative to mesh), 5 and reconstruction of the chest and abdominal wall. [6][7] It has also been successfully used for restoration of soft-tissue contours in the face and as a subdermal filler in augmentation rhinoplasty. 1,8 McCord et al have recently reported its use as a spacer graft in reconstructive and aesthetic eyelid surgery, where they found it to be a very satisfactory substitute for ear cartilage and fascia.…”