As a probe of circuit complexity in holographic field theories, we study subsystem analogues based on the entanglement wedge of the bulk quantities appearing in the "complexity = volume" and "complexity = action" conjectures. We calculate these quantities for one exterior region of an eternal static neutral or charged black hole in general dimensions, dual to a thermal state on one boundary with or without chemical potential respectively, as well as for a shock wave geometry. We then define several analogues of circuit complexity for mixed states, and use tensor networks to gain intuition about them. In the action approach, we find two possible cases depending on an ambiguity in the definition of the action associated with a counterterm. In one case, there is a promising qualitative match between the holographic action and what we call the purification complexity, the minimum number of gates required to prepare an arbitrary purification of the given mixed state. In the other case, the match is to what we call the basis complexity, the minimum number of gates required to prepare the given mixed state starting from a minimal complexity state with the same eigenvalue spectrum. One way to fix this ambiguity is to choose an action definition such that UV divergent part is positive, in which case the best match to the action result is the basis complexity. In contrast, the holographic volume does not appear to match any of our definitions of mixed-state complexity.