In this work, a novel 6D four-wing hyperchaotic system with a line equilibrium based on a flux-controlled memristor model is proposed. The novel system is inspired from an existing 5D four-wing hyperchaotic system introduced by Zarei (2015). Fundamental properties of the novel system are discussed, and its complex behaviors are characterized using phase portraits, Lyapunov exponential spectrum, bifurcation diagram, and spectral entropy. When a suitable set of parameters are chosen, the system exhibits a rich repertoire of dynamic behaviors including double-period bifurcation of the quasiperiod, a single two-wing, and four-wing chaotic attractors. Further analysis of the novel system shows that the multiple coexisting attractors can be observed with different system parameter values and initial values. Moreover, the feasibility of the proposed mathematical model is also presented by using Multisim simulations based on an electronic analog of the model. Finally, the active control method is used to design the appropriate controller to realize the synchronization between the proposed 6D memristive hyperchaotic system and the 6D hyperchaotic Yang system with different structures. The Routh–Hurwitz criterion is used to prove the rationality of the controller, and the feasibility and effectiveness of the proposed synchronization method are proved by numerical simulations.