Complication rates after chorionic villus sampling and midtrimester amniocentesis: A 7-year national registry study

Hsu, Wen Wei; Hsieh, Chia‐Jung; Lee, Chien‐Nan; Chen, Chih Ling; Lin, Ming; Kang, Jessica; Tai, Yi Yun; Huang, Kuan-Ying; Lin, Shu-Yung

doi:10.1016/j.jfma.2019.03.006

Cited by 17 publications

(7 citation statements)

References 20 publications

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“…26–28 Although preterm labor and pregnancy loss post-procedure are more commonly related to spontaneous rupture of membranes, infection has been described as an uncommon complication of reduction that may be associated with untimely fetal loss. 29 While chorionic villous sampling also carries a rare risk of procedure-related infection, 30,31 the prolonged time interval from sampling procedure at 14 weeks to clinical symptoms at 17 weeks precludes this possibility in this case.…”

Section: Discussionmentioning

confidence: 94%

Florid Bacillus cereus Infection of the Placenta Associated With Intrauterine Fetal Demise

et al. 2021

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Bacillus cereus is a gram-positive, rod-shaped bacterium that is commonly implicated in foodborne illness but has also become increasingly recognized as a source of serious non-gastrointestinal infections, including sepsis, meningitis, and pneumonia. Non-gastrointestinal B. cereus infections have been identified in children, especially in neonates; however, there are no previously described cases of fetal demise associated with B. cereus placental infection. We present a case of acute chorioamnionitis-related intrauterine fetal demise of twin A at 17 weeks gestation, noted two days after selective termination of twin B. Histological examination revealed numerous gram-positive bacilli in placental tissue, as well as fetal vasculature, in the setting of severe acute necrotizing chorioamnionitis and subchorionitis, intervillous abscesses, acute villitis, and peripheral acute funisitis. Cultures of maternal blood and placental tissue both yielded growth of B. cereus. This case underscores the importance of B. cereus as a human pathogen, and specifically demonstrates its potential as an agent of severe intraamniotic and placental infection with poor outcomes for the fetus.

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Section: Discussionmentioning

confidence: 94%

Florid Bacillus cereus Infection of the Placenta Associated With Intrauterine Fetal Demise

et al. 2021

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“…The highest chance of fetal loss: 1%-3% (attributable risk) TABLE 1: Invasive prenatal testing procedures and their associated risks. [6,7] NIPT is the method that detects the possibility of having genetic abnormalities or chromosomal disorders in a fetus. Non-invasive prenatal testing can only see a genetic condition's high and low risk.…”

Section: Cordocentesismentioning

confidence: 99%

Cell-Free Fetal Deoxyribonucleic Acid (cffDNA) Analysis as a Remarkable Method of Non-Invasive Prenatal Screening

Raj¹,

Yelne²

2022

Cureus

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The cell-free fetal DNA (cffDNA) analysis for screening fetal genetic anomalies has increased dramatically since its commercialization in 2011 worldwide. In the early weeks of pregnancy, it offers a hassle-free, noninvasive procedure of antenatal screening. It guides and protects mothers from undergoing unwanted riskladen invasive prenatal testing. cffDNA testing is accurate at detecting the abnormal fetus chromosome among a large pool population. Patau syndrome, Edward syndrome, and Down syndrome are currently being accurately screened by this method. Due to their sensitivity and specificity, they now have become the screening method of choice, approaching almost 100% in various studies with a large sample pool. The latest procedures to analyze cffDNA, like the new digital droplet polymerase chain reaction (ddPCR) and sophisticated next-generation sequencing (NGS), have increased detection rates with decreased analyzing time. The latest techniques make it possible to screen large numbers of the population with faster report generation. Screening for Rh incompatibility and its timely prevention is now more accessible and more accurate with the help of cffDNA analysis. The problem arises when we deviate from the primary disease and start testing for anomalies not intended to be screened by cffDNA in the first place. Fetal sex chromosome aneuploidy screening by cffDNA is one area where the test gives mixed results either due to differences in machinery, laboratory parameters, or human error. Other rare occurrences like trisomes, such as trisomy 7, trisomy 16, trisomy 22, and a few microdeletion syndromes are also being screened but with less accuracy. Like every technology, cffDNA analysis is not entirely free of criticism. Its high testing cost, potential to accurately prognosticate the gender of the developing fetus and absence of standard testing practices will become an issue as the test becomes routine worldwide.

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“…There are multiple case reports of bowel injury during amniocentesis resulting in septic shock and coagulopathy 21,22. Infection following amniocentesis is hypothesized to be as low as 0.05% 23. While these studies and case reports are limited to patients undergoing amniocentesis for fetal testing, these risks could be extrapolated to patients undergoing amniocentesis for inducing fetal demise.…”

Section: Clinical Benefits and Risks Of Use Of Feticidal Agentsmentioning

confidence: 99%

“…21,22 Infection following amniocentesis is hypothesized to be as low as 0.05%. 23 While these studies and case reports are limited to patients undergoing amniocentesis for fetal testing, these risks could be extrapolated to patients undergoing amniocentesis for inducing fetal demise. In summary, while serious maternal effects are rare in the limited literature on feticidal agent use in later abortion, current studies do suggest that there are potentially some risks and limited clinical benefits to utilizing feticidal agents, specifically digoxin before termination for D&E and induction abortion procedures.…”

Section: Feticidal Injection Agents Used In Dande and Induction Of La...mentioning

confidence: 99%

The Use of Feticidal Agents Before Dilation and Evacuation or Induction of Labor for Later Abortion

Nandi

Schultz

Roncari

2022

Clinical Obstetrics &Amp; Gynecology

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Abortion is a common medical procedure in the United States that is frequently the target of political and legal restrictions. These restrictions can negatively impact care and interfere with the patient-provider relationship. In this paper, we aim to review the historic context in which feticidal agents became more utilized in later abortion; describe current practices and protocols of using feticidal agents use for later abortion by dilation and evacuation and induction of labor; evaluate patient and provider perspectives on feticidal agent use; and propose areas of further ethical and research inquiry to characterize the use of these agents in later abortion procedures.

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Complication rates after chorionic villus sampling and midtrimester amniocentesis: A 7-year national registry study

Cited by 17 publications

References 20 publications

Florid Bacillus cereus Infection of the Placenta Associated With Intrauterine Fetal Demise

Florid Bacillus cereus Infection of the Placenta Associated With Intrauterine Fetal Demise

Cell-Free Fetal Deoxyribonucleic Acid (cffDNA) Analysis as a Remarkable Method of Non-Invasive Prenatal Screening

The Use of Feticidal Agents Before Dilation and Evacuation or Induction of Labor for Later Abortion

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