“…However, a significant number of patients developed allergic and/or toxic reactions to these products, resulting in diffuse corneal staining, bulbar and palpebral hyperemia, corneal infiltrates, and palpebral conjunctivitis. [2][3][4][5][6][7][8] As a result, manufacturers needed to develop products that provided effective kill against common ocular pathogens that accumulated on hydrogel contact lenses but that were safe to use on the ocular surface.…”