Complications of fine needle biopsy for focal liver lesions

Usefulness of Contrast-Enhanced Intraoperative Ultrasound Using Sonazoid in Patients With Hepatocellular Carcinoma

“…Resection of all detected FLLs is not necessarily beneficial for patients, and we have objected to performing needle biopsies, 30 which can cause complications and tumor seeding. [13][14][15] An FLL that shows no changes in tumor vascularity or lesion size for 12 months can be considered as being clinically "benign." 48 This reference standard for unresected FLLs was regarded as being suboptimal from a practical view point.…”

“…[10][11][12] Furthermore, a needle biopsy can induce tumor seeding [13][14][15] and ultimately worsen prognosis of patients. 16 Contrast-enhanced intraoperative ultrasound (CE-IOUS) using SonoVue (gaseous sulfur hexafluoride; Bracco, Italy) has been advocated as an alternative means of differentiating HCC from benign lesions among new focal liver lesions (FLLs) found using IOUS; this method is reportedly both useful and safe.…”

Estudio prospectivo sobre la utilidad de la ecografía de control tras la realización de pruebas invasivas hepáticas: biopsia hepática y punción aspiración con aguja fina (PAAF)

“…Aunque la incidencia real no se conoce, el riesgo de diseminación tumoral es de 0,006% aproximadamente (9). En nuestro caso dicha complicación no se ha tenido en cuenta ya que la diseminación tumoral se detecta generalmente de forma clínica a los meses o incluso años de la realización de la técnica y este no era el objetivo de nuestro estudio (10).…”

CT Imaging of Early Hepatocellular Carcinoma and the Natural Outcome of Hypoattenuating Nodular Lesions in Chronic Liver Disease

“…For differential diagnosis of early HCC from focal nodular hyperplasia and nodular regenerative hyperplasia, an imaging modality is helpful. Another possible risk of needle biopsy is needle tract seeding and intraperitoneal hemorrhage [21]. …”