“…Previous reports have described the risk factors associated with the development of flap complications, such as age, sex, tumor location, site of reconstruction, prior radiotherapy, and comorbidities, large tumor resections, cigarette packs smoked, and salvage procedures [3,15,18,19]. However, results were not similar in all series with some reports describing that complication rates were not associated with age, sex, smoking, preoperative radiotherapy, diabetes, or obesity [2,4,5,12].…”