Composition, and Anti‐Inflammatory and Antioxidant Activities of the Volatile Oil from the Fruit Peel of Garcinia brasiliensis

Abstract

The composition of the volatile oil obtained by hydrodistillation from the fruit peel of Garcinia brasiliensis (Mart.) Planch. et Triana was determined by GC/MS. A total of 38 components were identified, including gamma-muurolene (10.3%), spathulenol (8.7%), delta-cadinene (8.3%), torreyol (8.0%), alpha-cadinol (7.0%), cadalene (6.3%), and gamma-cadinene (5.3%). Oxygenated sesquiterpenes (43%) were the main group of compounds. The anti-inflammatory activity of the volatile oil was evaluated through the rat-paw edema model induced by carrageenan. Inhibition of the inflammatory process was noticed 3 h after carrageenan administration. In addition, the volatile oil showed poor antioxidant activity.

Anti-inflammatory and antinociceptive effects of Garcinia brasiliensis

“…In folk medicine, the leaves of Garcinia brasiliensis are used to treat tumors, inflammation of the urinary tract, arthritis and to relieve pain (Corrêa, 1978). As part of our continuous study of the Garcinia species, the volatile oil from the fruit-peel of Garcinia brasiliensis showed significant anti-inflammatory activity in the rat-paw edema model induced by carrageenan (Martins et al, 2008).…”

Topical anti-inflammatory constituents of lipophilic leaf fractions ofAlchornea floribundaandAlchornea cordifolia

“…AFLF and ACLF were found to exhibit significant ( p50.01) topical antiinflammatory activity. Lipophilic and volatile constituents from plants have been shown in several studies to possess anti-inflammatory activity (Kavimani, Karpagam, Jaykar, & Ilango, 1997;Kavimani, Vetrichelvan, Ilango, & Jaykar, 1996;Mariea, Dejanb, & Quetin-Leclercq, 2007;Martins et al, 2008;Shimizu et al, 1990;Souza, Siani, Ramos, Menezes-de-Lima, & Henriques 2003). The topical antiinflammatory activity may be related to the ability of the lipophilic constituent to permeate lipoidal skin layers.…”

Chemical&nbsp;Variability and&nbsp;Biological Activities of&nbsp;<em>Eucalyptus</em> spp. Essential Oils

“…The use of essential oils has been considered an alternative to overcome food deterioration problems faced by food industry [157,177]. Natural products presenting antioxidant activity has also been taken into consideration since compounds with antioxidant activity can also be utilized as antimicrobial ones [37,178].…”