Composition and antimicrobial activity of the essential oil of six Hypericum species from Serbia

Saroglou, Vasiliki; Marin, Petar D.; Rancic, Ana; Veljić, Milan; Skaltsa, Helen

doi:10.1016/j.bse.2006.09.009

Cited by 93 publications

(60 citation statements)

References 15 publications

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“…Considering the chemical composition of the essential oil, they contain less phenolic components and oxygenation terpenoid than H. brevipes. Previous results showed that greater antimicrobial potential could be ascribed to the oxygenated terpenes (Devi et al, 2010;Saroglou et al, 2007).…”

Section: Antimicrobial Activitymentioning

confidence: 97%

The essential oils chemical compositions and antimicrobial, antioxidant activities and toxicity of threeHyptisspecies

Huang

Jiang

et al. 2013

Pharmaceutical Biology

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Context: Hyptis suaveolens (Linn.) Poit., Hyptis rhomboidea Mart. et Gal., and Hyptis brevipes Poit., are three species of Hyptis Jacq. (Lamiaceae). Hyptis suaveolens is used for the treatment of fever, headache, gastrointestinal bloating and rheumatism in the traditional folk medicine; Hyptis rhomboidea for hepatitis, ulcer and swollen poison; and Hyptis brevipes for asthma and malaria. Objective: To characterize chemical compositions of the oils from three Hyptis species and evaluate their potential antimicrobial, radical scavenging activities and toxicities against brine shrimp. Materials and methods: The oils were obtained by hydrodistillation, and their chemical compositions were investigated by gas chromatography-mass spectrometry (GC-MS). Minimum inhibitory concentrations (MICs) were determined using the tube double-dilution technique. The antioxidant activities were investigated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay and toxicities by the brine shrimp bioassay. Results: Forty-seven, 33 and 28 constituents of oils isolated, respectively, from H. suaveolens, H. rhomboidea and H. brevipes were identified. Among the essential oils, the strongest antioxidant activity was exhibited by H. brevipes with an SC 50 value of 2.019 AE 0.25 mg mL À1. The H. brevipes oil exhibited the strongest antimicrobial activity (3.125-6.25 mg mL À1) on pathogens employed in the assay. They all showed significant toxicities with median lethal concentration (LC 50 ) values of 62.2 AE 3.07 mg mL À1, 65.9 AE 6.55 mg mL À1 and 60.8 AE 9.04 mg mL À1, respectively. Discussion and conclusions: The three Hyptis species oils possess strong antimicrobial activities and toxicities. Hyptis rhomboidea and H. brevipes showed considerable antioxidant activity compared to the positive control.

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Section: Antimicrobial Activitymentioning

confidence: 97%

The essential oils chemical compositions and antimicrobial, antioxidant activities and toxicity of threeHyptisspecies

Huang

Jiang

et al. 2013

Pharmaceutical Biology

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“…Among the previous studies about Hypericum essential oils from Turkey, many taxa were characterized by the high amount of α-pinene [11,20,[22][23][24][25][26][27][28][29][30] [21]. α-pinene, baeckeol, limonene and spathulenol were identified as major components in H. thymopsis, although baeckeol and limonene were not determined in a previous study.…”

Section: Resultsmentioning

confidence: 96%

Essential Oil Composition of Five Endemic Hypericum Species from Turkey

2013

Med Aromat Plants

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“…Wide scope research has been done concerning H. perforatum and H. maculatum growing wild in Lithuania. Data collected investigating Lithuanian populations of Hypericum mainly concern morphology and chemistry [25,20,21,15,17]. In other countries the genetic diversity of Hypericum is precisely characterized and species specific markers of H. perforatum have been identified [18,6], chloroplast DNA variability among some Hypericum species has also been documented [7].…”

Section: Introductionmentioning

confidence: 99%

Adoption of RAPD-related methodology for analyses of Hypericum maculatum Crantz growing wild in Lithuania

Zybartaitė¹,

Žukauskienė²,

Kupčinskienė³

et al. 2011

Biologija

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Hypericum genus plants are widespread all over Europe and Asia and they are one of the most important world plants used for medicinal purposes. In Lithuania insufficient attention is paid to the second according to the abundance species of Hypericum genus -H. Maculatum L. Till now research of this species was mainly concentrated on morphology and some chemical parameters. The present study aimed at selection of the conditions for random amplification of polymorphic DNA extracted from H. maculatum growing wild in Lithuania. NucleoSpin Plant II (Macherey-Nagel, Germany) as the most efficient kit was selected for DNA extraction from H. maculatum. For polymerase chain reaction (PCR) 14 nucleotide primers (Biomers.net, Germany) were used and OP-A1, OP-A4, OP-A9, OP-B12, OP-B19, OP-C6a, OP-C7a, OP-C11, OP-C19, OP-D20, OP-Q2 were selected for further studies of genetic diversity of populations of H. maculatum (OP-B13, OP-D19a, OP-Q11 were rejected). DNA amplification program with 40 cycles was chosen from 35, 40 and 45 cycles tested. Among two different composition mixes used for PCR, more efficient was the one consisting of: 0.05 U/µl Taq DNA polymerase; 1 × Taq buffer; 1.5 nM MgCl 2 ; 0.2 mM dNTP; 2 µl primer (10 pmol/µl) and 14.55 µl deionised water (Fermentas, Lithuania). For preparation of above mentioned mix 3 different types of Taq buffer were tested: 1 -Taq buffer with KCl; 2 -Taq buffer with (NH 4 ) 2 SO 4 ; 3 -Taq buffer without detergent. The best results were achieved with the first buffer.

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Composition and antimicrobial activity of the essential oil of six Hypericum species from Serbia

Cited by 93 publications

References 15 publications

The essential oils chemical compositions and antimicrobial, antioxidant activities and toxicity of threeHyptisspecies

The essential oils chemical compositions and antimicrobial, antioxidant activities and toxicity of threeHyptisspecies

Essential Oil Composition of Five Endemic Hypericum Species from Turkey

Adoption of RAPD-related methodology for analyses of Hypericum maculatum Crantz growing wild in Lithuania

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