Composition and reactivity of aminolysis products of phenyl glycidyl ether with benzylamine

Investigating the reliability and interpretability of machine learning frameworks for chemical retrosynthesis

“…The epoxide can be nucleophilically attacked by the amine. 73 For this reaction to happen, the epoxide needs to be fixed in orientation for the correct alcohol to be released. Thus, the greatest challenge lies in maintaining exact stereocontrol.…”