Composition of a Monoterpenoid-rich Essential Oil from the Rhizome of <i>Zingiber officinale</i> from North Western Himalayas

Gupta, Suphla; Pandotra, Pankaj; Ram, G.; Anand, Rajneesh; Gupta, Ajai Prakash; Husain, Kashif; Bedi, Yashbir S.; Mallavarapu, Gopal R.

doi:10.1177/1934578x1100600122

Cited by 19 publications

(20 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In another study performed for ginger cultivated in different regions of India, the results varied over a large range from 0.06 to 0.6 mg/kg DM [20]. In ginger cultivated in Ethiopia and Nigeria, the concentration of lead is below the detection level [13,34].…”

Section: Resultsmentioning

confidence: 99%

Application of Chromatographic and Spectroscopic Methods towards the Quality Assessment of Ginger (Zingiber officinale) Rhizomes from Ecological Plantations

Koch

Kukuła-Koch

Marzec

et al. 2017

IJMS

View full text Add to dashboard Cite

The usefulness of ginger in the food industry and pharmacotherapy is strictly related to its content of various components. The study elucidates the chemical composition of Zingiber officinale rhizomes cultivated on ecological plantations on Shikoku Island (Japan). GC-MS analysis of terpene content, LC-MS determination of phenolic content, and the determination of 12 elements using AAS spectrometry were performed to give more detailed insight into the samples. Ninety-five percent of terpene composition was elucidated, with zingiberene as the most abundant sesquiterpene (37.9%); the quantification of gingerols and shogaols was performed, showing the highest contribution of 6-gingerol (268.3 mg/kg); a significant K (43,963 mg/kg of dry mass) and Mn (758.4 mg/kg of dry mass) content was determined in the elemental analysis of the rhizomes and low concentration of toxic elements (Cd, Ni and Pb) remaining below the safe level values recommended by European Commission Directives. The main phenolic compound was (6)-gingerol, which is characteristic of fresh rhizomes and is responsible for their taste and aroma. Surprisingly, high amounts of (6)-shogaol were determined, even though this phenolic compound usually occurs in old or processed material and not in fresh rhizomes. Sesquiterpenes were the major fraction of volatiles. The highest concentrations were determined for α-zingiberene, β-sesquiphellandrene, (E,E)-α-farnesene, geranial, and ar-curcumene. The volatiles composition of ginger cultivated on Shikoku Island is specific and strongly differs from plants cultivated in China, Nigeria, or Australia. The elemental composition of ginger rhizomes grown in ecological plantations is more beneficial for human health compared to products grown in normal cultivars, as the products contain high amounts of potassium and manganese and are characterized by low sodium content and lower levels of toxic heavy metals.

show abstract

Section: Resultsmentioning

confidence: 99%

Application of Chromatographic and Spectroscopic Methods towards the Quality Assessment of Ginger (Zingiber officinale) Rhizomes from Ecological Plantations

Koch

Kukuła-Koch

Marzec

et al. 2017

IJMS

View full text Add to dashboard Cite

show abstract

“…Sesquiterpenes are major constituents of the essential oils of turmeric (ar-turmerone, α-turmerone and ß-turmerone) 10 and ginger (zingiberene and ar-curcumene) [34-43], while the monoterpene isomers, neral and geranial, collectively referred to as citral, are only present in GEO and comprise a variable but significant amount by weight (16-75%) [35,37,39-43]. Because estrogenic effects have been reported previously for citral in vitro [17,18], including low affinity estrogen receptor (ER) binding and estrogenic activity, the in vivo effects of GEO were compared to those of 17ß-estradiol in the SCW model.…”

Section: Discussionmentioning

confidence: 99%

Anti-inflammatory effects of the essential oils of ginger (Zingiber officinale Roscoe) in experimental rheumatoid arthritis

et al. 2016

View full text Add to dashboard Cite

Ginger and its extracts have been used traditionally as anti-inflammatory remedies, with a particular focus on the medicinal properties of its phenolic secondary metabolites, the gingerols. Consistent with these uses, potent anti-arthritic effects of gingerol-containing extracts were previously demonstrated by our laboratory using an experimental model of rheumatoid arthritis, streptococcal cell wall (SCW)-induced arthritis. In this study, anti-inflammatory effects of ginger's other secondary metabolites, the essential oils (GEO), which contain terpenes with reported phytoestrogenic activity, were assessed in female Lewis rats with SCW-induced arthritis. GEO (28 mg/kg/d ip) prevented chronic joint inflammation, but altered neither the initial acute phase of joint swelling nor granuloma formation at sites of SCW deposition in liver. Pharmacologic doses of 17-β estradiol (200 or 600 μg/kg/d sc) elicited the same pattern of anti-inflammatory activity, suggesting that GEO could be acting as a phytoestrogen. However, contrary to this hypothesis, GEO had no in vivo effect on classic estrogen target organs, such as uterus or bone. En toto, these results suggest that ginger's anti-inflammatory properties are not limited to the frequently studied phenolics, but may be attributable to the combined effects of both secondary metabolites, the pungent-tasting gingerols and as well as its aromatic essential oils.

show abstract

“…On the other hand, the study revealed higher percentage of geranial (14.3%) and geraniol (7.3%) [5a]. The study of chemical composition of ginger essential oil from India discovered the large amounts of monoterpenes with lower percentage of 1.8-cineole (10.9%) and higher percentage of geraniol (14.5%) [13]. Another study of ginger essential oil from Ecuador similarly revealed the high percentage of monoterpenes such as citral in contrast to the chemical compound commonly contained in the essential oil of ginger [14].…”

mentioning

confidence: 99%

Chemical Analysis of Red Ginger (Zingiber officinale Roscoe var rubrum) Essential Oil and Its Anti-biofilm Activity against Candida albicans

Rinanda

Isnanda

Zulfitri

2018

Natural Product Communications

View full text Add to dashboard Cite

Biofilm formation is one of the virulence factors of Candida albicans, contributing to the development of resistance to various antifungal drugs. In order to combat resistant microbes such as C. albicans, the discovery and development of antifungal substances must explore the anti-biofilm activity of substances, which are extracted from traditional medicinal plants widely available in tropical countries such as Indonesia. One of the natural ingredients that can be developed is red ginger. This plant has been used empirically in the treatment of various infectious diseases, including fungal infections. The aim of this study is to determine the composition of chemical compounds in the essential oil of the red ginger rhizomes planted in Aceh, Indonesia and the anti-biofilm activity of the essential oil against C. albicans, isolated from a clinical sample. The chemical analysis of the essential oil was performed by Gas Chromatography-Mass Spectrophotometry (GC-MS). Anti-biofilm activity was observed through biofilm inhibition and degradation activities, determined by Cristal Violet assay. Data were analyzed using ANOVA test and Duncan's post hoc test with 99% CI. The GC-MS results showed that the essential oil used in this study contained high monoterpenes (60.55%) which is dominated by E-citral/geranial (11.97%) and 1.8-cineole (15.10%). The highest sesquiterpenes derivative was αrcurcumene (16.86%). The significant inhibition of C. albicans biofilm formation was obtained at a concentration of 0.5% and the biofilm degradation was obtained at a concentration of 0.125%. The data indicates that the high monoterpenoids-red ginger essential oil used in this study has performed significant anti-biofilm activity against C. albicans.

show abstract

Composition of a Monoterpenoid-rich Essential Oil from the Rhizome of Zingiber officinale from North Western Himalayas

Cited by 19 publications

References 12 publications

Application of Chromatographic and Spectroscopic Methods towards the Quality Assessment of Ginger (Zingiber officinale) Rhizomes from Ecological Plantations

Application of Chromatographic and Spectroscopic Methods towards the Quality Assessment of Ginger (Zingiber officinale) Rhizomes from Ecological Plantations

Anti-inflammatory effects of the essential oils of ginger (Zingiber officinale Roscoe) in experimental rheumatoid arthritis

Chemical Analysis of Red Ginger (Zingiber officinale Roscoe var rubrum) Essential Oil and Its Anti-biofilm Activity against Candida albicans

Contact Info

Product

Resources

About