Composition of the Volatile Components Extracted from the Roots of &amp;lt;i&amp;gt;Scorzonera undulata&amp;lt;/i&amp;gt; ssp &amp;lt;i&amp;gt;deliciosa&amp;lt;/i&amp;gt; (Guiss) Maire: From Algeria

Brahim, Harkati; Akkal, Salah; Marie, Genevieve Dijoux Franca

doi:10.4236/gsc.2012.22010

Cited by 6 publications

(5 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…deliciosa. The role of these phytochemical components in counteracting oxidative stress, microbial and fungal growth, and many health disorders has been approved (Erden et al, 2013;Harkati et al, 2010;Mzid et al, 2017). Herein, halves of DPPH radical and the ferric reducing potential were inhibited at concentrations ranging from 0.1 to 0.25 mg × mL −1 that were close to what has been recently reported (Badraoui et al, 2020;Rahmouni et al, 2022).…”

Section: Discussionsupporting

confidence: 73%

Phytochemical Composition, Bioavailability and Pharmacokinetics of Scorzonera undulata Methanolic Extracts: Antioxidant, Anticancer, and Apoptotic Effects on MCF7 Cells

Bédoui,

Nasr,

Ksouda

et al. 2023

Pharmacognosy Magazine

View full text Add to dashboard Cite

Background Finding new effective substances to develop drugs against cancer or to prevent it remains a big challenge facing scientists and clinicians. Objectives In such an issue, we tested the anti-tumoral effect of Scorzonera undulata extracts on MCF7 cells. Materials and Methods Methanolic extracts of S. undulata roots (RSU) and aerial parts (ASU) from the Ha’il region were analyzed by HPLC. Their DPPH scavenging, ferric-reducing antioxidant power (FRAP) and total antioxidant potentials were evaluated. The MTT test was used to determine their cytotoxic effects on MCF7 cells using different concentrations, and their potential to induce apoptosis was determined by measuring the mitochondrial transmembrane loss of potential by flow cytometry using the JC-1 fluorescent marker. Results S. undulata was found to be rich in flavonoids, tannins, and polyphenols. ASU contains great amounts of apigenin and gallic acid, whereas RSU contains luteolin and chlorogenic acid as major components. The potential to scavenge DPPH and the total antioxidant activity of ASU were twofold greater than those of RSU. MCF7 cell viability was reduced by 50% at concentrations of 4.22 ± 0.06 and 5.89 ± 0.08 mg.mL−1, respectively, for ASU and RSU at 24 h. In addition, S. undulata extracts induced MCF7 cells’ death through cell lysis and apoptosis. Conclusion As an edible vegetable, S. undulata is worth further exploration in alternative and complementary medication as it possesses significant antioxidant and anticancer potentials.

show abstract

Section: Discussionsupporting

confidence: 73%

Phytochemical Composition, Bioavailability and Pharmacokinetics of Scorzonera undulata Methanolic Extracts: Antioxidant, Anticancer, and Apoptotic Effects on MCF7 Cells

Bédoui,

Nasr,

Ksouda

et al. 2023

Pharmacognosy Magazine

View full text Add to dashboard Cite

show abstract

“…Fatty acid profiling studies on the genus are scarce. Recent literature review showed only a few studies subjecting fatty acids of the genus [21–25] . Species evaluated in these studies are Scorzonera paradoxa Fisch and CA Mey., S. undulata ssp deliciosa (Guiss) Maire, S. hieraciifolia Hayek., S. hispanica L., S. divaricata Turcz and S. tomentosa L. The results of the current study are in accordance with these studies which show that these species contain both saturated and unsaturated fatty acids namely oleic acid, linoleic acid, palmitic acid, stearic acid and myristic acid.…”

Section: Resultsmentioning

confidence: 99%

Terpenoid and Fatty Acid Profiling along with Anti‐Tyrosinase and Anti‐Urease Potentials of Scorzonera pygmaea Sibth. & Sm. an Endemic Plant of Turkey

Şahin

Boğa

Sarı

2022

Chemistry & Biodiversity

View full text Add to dashboard Cite

Petroleum ether (PE), chloroform (CH), ethyl acetate (EA) and butanol (BU) fractions were obtained from ethanol extracts of the roots (SPR) and the above ground (SPH) parts of S. pygmaea. PE fractions were evaluated by GC/MS for profiling the terpenoids and the fatty acids of the plant. 29 compounds in total including saturated (major palmitic acid), unsaturated (major linoleic acid) fatty acids and triterpenes were tentatively determined. Short‐term extraction methods might be preferred to avoid esterification of fatty acids. Phytochemical profiles of SPR‐PE and SPH‐PE were found to be similar to each other and to other few Scorzonera species reported previously. These results will contribute to the chemotaxonomic studies about the genus which is considered taxonomically complex genus. Activity studies were carried out using kojic acid (87.10 % inhibition) standard for tyrosinase and thiourea (95.83 % inhibition) standard for urease. SPR‐CH was determined as the most potent fraction with 55.94 % and 55.10 % inhibition of tyrosinase and urease, respectively at the same concentration of the standards (200 microgram/mL). These moderate results might be considered encouraging for more detailed studies to determine the active compounds and to evaluate the plant's potential in pharmaceutical, food and cosmetic industries in terms of tyrosinase and urease inhibition.

show abstract

“…Other researchers have also shown that MeOH is a better solvent for extraction of flavonoids than other solvents such as EtOH, acetone, and DCM [27]. In addition, in a comparative study conducted by Ghasmezadeet et al [28] on the total flavonoid content of Scorzonera species the extraction capacity of MeOH was shown to be higher than that of acetone. Another study conducted to isolate and identify the flavonoids contained in nine taxa of Scorzonera species (S. austriaca Willd.…”

Section: Resultsmentioning

confidence: 92%

Chemical Composition, Antioxidant, and Anti-Diabetic Activities of Scorzonera phaeopappa Boiss

El Hosry,

Al Ayash,

Matar Boumosleh

et al. 2023

Stresses

View full text Add to dashboard Cite

Wild edible plants have attracted increasing interest from researchers because of their richness in biologically active phytochemicals. These are found to be a potential remedy for oxidative-stress-mediated diseases such as diabetes mellitus. In this study, total phenol, total terpene, and total flavonoid content as well as antioxidant and antidiabetic activities of Scorzonera phaeopappa Boiss from Lebanon were determined. Using dichloromethane, dichloromethane ammonia, methanol, acetone, and ethanol, extracts were prepared from the edible leaves. The antioxidant activity and the antidiabetic activity were determined by 2,2-diphenyl-1-picrylhydrazyl scavenging, Fe2+-chelating and α-amylase/α-glucosidase inhibitory assays, respectively. Dichloromethane ammonia was found to have the highest extraction capacity on phenols (2.73 mg GAE /100 mg extract) and terpenes (232.42 mg LE/100 mg extract). Methanol was found to have the highest extraction capacity on total flavonoids (63.05 mg QE/100 mg extract). The methanol extract exhibited the highest DPPH scavenging activity (IC50 0.07 mg/mL) and the highest chelating activity as compared to other extracts (0.08 mg/mL, chelating activity 50%). The acetone extract was two times more active than acarbose against α-amylase enzyme and was the most active against α-glucosidase (6.3 mg/mL). Significant positive correlations were observed between total phenol content and α-glucosidase inhibitory assay and total terpene content and α-glucosidase inhibitory assay.

show abstract

Composition of the Volatile Components Extracted from the Roots of <i>Scorzonera undulata</i> ssp <i>deliciosa</i> (Guiss) Maire: From Algeria

Cited by 6 publications

References 3 publications

Phytochemical Composition, Bioavailability and Pharmacokinetics of Scorzonera undulata Methanolic Extracts: Antioxidant, Anticancer, and Apoptotic Effects on MCF7 Cells

Phytochemical Composition, Bioavailability and Pharmacokinetics of Scorzonera undulata Methanolic Extracts: Antioxidant, Anticancer, and Apoptotic Effects on MCF7 Cells

Terpenoid and Fatty Acid Profiling along with Anti‐Tyrosinase and Anti‐Urease Potentials of Scorzonera pygmaea Sibth. & Sm. an Endemic Plant of Turkey

Chemical Composition, Antioxidant, and Anti-Diabetic Activities of Scorzonera phaeopappa Boiss

Contact Info

Product

Resources

About