Comprehensive evaluation of imidazole-based polymers for the enrichment of selected non-steroidal anti-inflammatory drugs

Schemeth, Dieter; Kappacher, Christoph; Rainer, Matthias; Thalinger, Ramona; Bonn, Günther K.

doi:10.1016/j.talanta.2016.03.015

Cited by 27 publications

(9 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our previous studies, we reported the adsorption capacity of the poly(ethylene glycol dimethacrylate-n-vinyl imidazole) [poly(EGDMA-VIM)] beads for Cr(VI) [31], Hg(II), Cd(II), and Cu(II) [32] as well as its immobilization of tyrosinase [33], yeast invertase [34], and α-amylase [35] on Cu 2+ chelated [poly(EGDMA-VIM)] beads. Additionally, the poly(ethylene glycol dimethacrylate-co-vinylimidazole) was used for removal of Cd 2+ [36], and Pb 2+ [37] as well as the solid phase extraction of selected non-steroidal anti-inflammatory drugs [38] and purification and isolation of phenolic acids [39]. Furthermore, PEGMA-VI microspheres were used as an adsorbent for removal of Cu(II) [40], Cr(VI), and Ni(II) [41].…”

Section: İ öZdemir Et Al / Desalination and Water Treatment 159 (20mentioning

confidence: 99%

Synthesis and characterization of polymer microspheres and its application for phenol adsorption

Özdemir¹,

Kara²,

Tekin³

et al. 2019

Desalination and Water Treatment

View full text Add to dashboard Cite

This paper reports synthesis of the poly(ethylene glycol dimethacrylate-n-vinyl imidazole) ([poly(EGDMA-VIM)]) microspheres by suspension polymerization for the removal of phenol from an aqueous solution. The synthesized [poly(EGDMA-VIM)] microspheres were characterized by various analysis techniques. The [poly(EGDMA-VIM)] microspheres possessed a high specific surface area (304.4 m 2 g −1). It was found that the pseudo-second-order kinetic and Freundlich isotherm models could well define the phenol adsorption process. The maximum capacity of the [poly(EGD-MA-VIM)] microspheres was calculated to be 34.7441 mg g −1 at 298 K and natural pH from Langmuir isotherm. The adsorption thermodynamics revealed that the adsorption of phenol was an exothermic and spontaneous process. The [poly(EGDMA-VIM)] microspheres were easily regenerated by using a 0.01 M NaOH solution, and were repeatedly used for at least 5 cycles without losing the adsorption capacity. The experimental results suggest that the [poly(EGDMA-VIM)]microspheres can be implemented as a promising adsorbent for phenol removal from wastewater.

show abstract

Section: İ öZdemir Et Al / Desalination and Water Treatment 159 (20mentioning

confidence: 99%

Synthesis and characterization of polymer microspheres and its application for phenol adsorption

Özdemir¹,

Kara²,

Tekin³

et al. 2019

Desalination and Water Treatment

View full text Add to dashboard Cite

show abstract

“…The suspension polymerization of N ‐vinyl imidazole cross‐linked with divinylbenzene or ethylene glycol dimethacrylate generated two hydrophilic sorbents applicable for the isolation and enrichment of non‐steroidal anti‐inflammatory drugs . The obtained stationary phases were used for SPE experiments and a part of the prepared sorbents was further modified with methyl iodide to convert it into strong anion‐exchange sorbents that interacted more strongly with non‐steroidal anti‐inflammatory drugs.…”

Section: Polymeric Mixed‐mode Stationary Phasesmentioning

confidence: 99%

Recent advances in mixed‐mode chromatographic stationary phases

Sýkora

Řezanka

Záruba

et al. 2018

J of Separation Science

View full text Add to dashboard Cite

Mixed‐mode phases have become very popular in the last decade, and the number of new mixed/multi‐mode sorbents is growing fast. Unlike single‐mode stationary phases, perfectly suited for the separation of the analytes possessing similar physicochemical properties, for instance reversed‐phase chromatography for hydrophobic solutes, mixed‐mode sorbents providing multimodal interactions can render better separation selectivity for complex mixtures of solutes differing significantly in their physicochemical characteristics. The most frequent modern mixed‐mode stationary phases are di/tri‐mode sorbents embracing the following interactions, hydrophobic, electrostatic (coulombic), and hydrophilic. According to their structures, it is possible to distinguish silica‐based, polymer‐based, hybrid, and monolithic mixed‐mode stationary phases. Herewith, newly synthesized mixed‐mode sorbents developed within the last two and half years are categorized, discussed, and summarized. The main attention is devoted to the description of the synthetic routes and characterization methods applied for the new stationary phases.

show abstract

“…Recent studies revealed that the substituted imidazole derivatives have attracted much attention due to their broad spectrum of pharmacological activities such as anti-inammatory, antifungal, anticonvulsant. [56][57][58] A series of novel aminosubstituted xantheno[1,2-d]imidazole derivatives have been designed and synthesized and their antiproliferative activity has been evaluated against human breast MDA-MB-231 cell line. Compounds 49-52 with IC 50 value of 46 mM, 28 mM, 16 mM and 18 mM respectively (Table 4) exhibited the highest antiproliferative activity of all the compounds tested.…”

Section: The Imidazole Functional Groupmentioning

confidence: 99%