Comprehensive Gas Chromatography: Food and Metabolomocs Applications

Abstract

Since the comprehensive two-dimensional gas chromatography (GC × GC) technique is becoming more and more available for scientists as well as for laboratories performing routine analyses, the most successful field of applications are petrochemical, food and essential oil analysis. However, this technique coupled with TOF-MS (P.1, l. 27) could be even more successfully used in the field of metabolomics. The review presents briefly the concept of comprehensive 2D GC and the principles of the technique. Certain specific applications are discussed to show the usefulness of GC × GC combined with different detectors for determination of compounds not always easy to measure with other techniques.

Comprehensive Two-Dimensional Gas Chromatography Advances in Technology and Applications: Biennial Update

“…The applications of GC×GC are numerous, and they continue to grow as this technique establishes its role as a tool to resolve complex samples. Several reviews − ,,,,− ,− in the last 2 years have explored applications of this tool, focusing on a number of different fields, as previously discussed. Thus, we gather here some of the key and most recent applications, highlighting relevant areas of interest (Figure ).…”

“…Nolvachai et al 15 also considered the role of MDGC in food analysis, with food-focused GC×GC literature reviewed. Straczynski and Ligor 16 briefly reviewed the principles of GC×GC and then introduced its role for various food samples, food flavor such as honey, essential oils, and contamination largely from polyaromatic hydrocarbons (PAH) and polychlorinated biphenyls (PCB), and about 10 studies on metabolomics studies of disease and spoilage. Metabolomics reviews continued with Higgins Keppler et al, 17 who reviewed advances in GC×GC method development with respect to its increasing use for metabolomics, reporting aspects of GC×GC related to sampling techniques, discoveries in metabolomic profiling, and recommended best practices for curating metabolomics data.…”