Comprehensive study of an optical fiber plasmonic microsensor in a microfluidic device

Makiabadi, Tahereh; Nader, Victor Le; Kanso, Malak; Louarn, G.

doi:10.1051/epjap/2011100223

Cited by 1 publication

(1 citation statement)

References 15 publications

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“…The resolution of the refractive index of various sucrose solutions was enhanced by 2.4-fold in the microfluidic system. Makiabadi et al also integrated an optical fiber SPR sensor with a microfluidic system to monitor in real-time the sensitivity of OFS for each kinetic reaction occurring at the surface [ 35 ]. In this paper, we combined a curved D-type optical fiber sensor with a microfluidic chip for sensing bio-liquids with different refractive indices.…”

Section: Introductionmentioning

confidence: 99%

Integration of Curved D-Type Optical Fiber Sensor with Microfluidic Chip

Sun

Hsu

2016

Sensors

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A curved D-type optical fiber sensor (OFS) combined with a microfluidic chip is proposed. This OFS, based on surface plasmon resonance (SPR) of the Kretchmann’s configuration, is applied as a biosensor to measure the concentrations of different bio-liquids such as ethanol, methanol, and glucose solutions. The SPR phenomenon is attained by using the optical fiber to guide the light source to reach the side-polished, gold-coated region. Integrating this OFS with a polymethylmethacrylate (PMMA)-based microfluidic chip, the SPR spectra for liquids with different refractive indices are recorded. Experimentally, the sensitivity of the current biosensor was calculated to be in the order of 10−5 RIU. This microfluidic chip-integrated OFS could be valuable for monitoring subtle changes in biological samples such as blood sugar, allergen, and biomolecular interactions.

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Section: Introductionmentioning

confidence: 99%