Computational method for the optimization of quasimonoenergetic laser Compton x-ray sources for imaging applications

Effarah, Haytham H.; Reutershan, Trevor; Lagzda, Agnese; Hwang, Yoonwoo; Hartemann, F. V.; Barty, C. P. J.

doi:10.1364/ao.444307

Cited by 3 publications

(1 citation statement)

References 34 publications

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“…The notebook outputs a 4-dimensional array with values for the scattered x-ray angle in x, angle in y, energy and intensity. This calculation was performed for 3 different energy tunings of the electron beam and used as input into Compton FastFit [12] to quickly scan over electron energy during optimization.…”

Section: Calculation Of the Laser-compton Scattering X-ray Spectrummentioning

confidence: 99%

Bayesian optimization of laser-Compton x-ray sources for medical imaging applications

Reutershan

Effarah

Barty

2023

Medical Imaging 2023: Physics of Medical Imaging

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Laser-Compton x-ray sources have many advantages over traditional x-ray tubes for use in medical imaging due to their monoenergetic energy spectrum, tunability, high-flux, and low-dose potential. These properties can specifically be taken advantage of in the context of K-edge subtraction (KES) imaging. Previous optimization approaches are time-consuming by scanning over high-dimensional parameter spaces. Here, we show how a Bayesian optimization routine optimizes LCS source parameters in only a fraction of the computational time. Using this approach, we found a configuration that produces non-inferior image quality in KES mammography compared to a previously optimized direct energy tuning technique. Moreover, a successfully optimized implementation of scanning K-edge subtraction imaging was realized applying this Bayesian approach.

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Section: Calculation Of the Laser-compton Scattering X-ray Spectrummentioning

confidence: 99%

Bayesian optimization of laser-Compton x-ray sources for medical imaging applications

Reutershan

Effarah

Barty

2023

Medical Imaging 2023: Physics of Medical Imaging

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Effect of the local energy distribution of x-ray beams generated through inverse Compton scattering in dual-energy imaging applications

Paternò,

Cardarelli,

Fantoni

et al. 2023

Appl. Opt.

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X-ray sources based on the inverse Compton interaction between a laser and a relativistic electron beam are emerging as a promising compact alternative to synchrotron for the production of intense monochromatic and tunable radiation. The emission characteristics enable several innovative imaging techniques, including dual-energy K-edge subtraction (KES) imaging. The performance of these techniques is optimal in the case of perfectly monochromatic x-ray beams, and the implementation of KES was proven to be very effective with synchrotron radiation. Nonetheless, the features of inverse Compton scattering (ICS) sources make them good candidates for a more compact implementation of KES techniques. The energy and intensity distribution of the emitted radiation is related to the emission direction, which means different beam qualities in different spatial positions. In fact, as the polar angle increases, the average energy decreases, while the local energy bandwidth increases and the emission intensity decreases. The scope of this work is to describe the impact of the local energy distribution variations on KES imaging performance. By means of analytical simulations, the reconstructed signal, signal-to-noise ratio, and background contamination were evaluated as a function of the position of each detector pixel. The results show that KES imaging is possible with ICS x-ray beams, even if the image quality slightly degrades at the detector borders for a fixed collimation angle and, in general, as the beam divergence increases. Finally, an approach for the optimization of specific imaging tasks is proposed by considering the characteristics of a given source.

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Path to 100 fs multi-MeV gamma rays from extremely brilliant Compton sources

Reutershan,

Hwang,

Effarah

et al. 2023

Ultrafast Optics 2023 - UFOXIII

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Computational method for the optimization of quasimonoenergetic laser Compton x-ray sources for imaging applications

Cited by 3 publications

References 34 publications

Bayesian optimization of laser-Compton x-ray sources for medical imaging applications

Bayesian optimization of laser-Compton x-ray sources for medical imaging applications

Effect of the local energy distribution of x-ray beams generated through inverse Compton scattering in dual-energy imaging applications

Path to 100 fs multi-MeV gamma rays from extremely brilliant Compton sources

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