Computational studies on the copper(II) catalyzed Michael reaction

Copper Nanoparticles in Ionic Liquid: An Easy and Efficient Catalyst for Selective Carba-Michael Addition Reaction

“…Copper nanoparticles are highly efficient for the aza-Michael addition and thia-Michael addition reaction and they have been used in organic solvents which are very toxic in nature [18][19][20][21] Copper nanooparticles in ionic liquid A attractive, being cheap (they can be prepared from Cu(NO 3 ) 2 , are high yielding, need mild reaction conditions and are recyclable. Rothenberg and co-workers have recently reported the use of copper nanoparticles, which are less harmful to the environment than any other metals in Suzuki cross coupling reactions [20,21].…”

“…Rothenberg and co-workers have recently reported the use of copper nanoparticles, which are less harmful to the environment than any other metals in Suzuki cross coupling reactions [20,21]. Ionic liquids have been employed as reaction media for several organic reactions, namely alkylation [22], hydrogenation [23], oxidation [24][25][26].…”

Theoretical Study of Hydrated Copper(II) Interactions with Guanine: A Computational Density Functional Theory Study

“…Coordination and stability of Cu(II) and Zn(II) complexes with adenosine and cytidine were investigated by Gasowska and Lomozik . A theoretical study on the copper(II)-catalyzed Michael reaction was published by Borowka and van Wullen where the enamine was deprotonated upon coordination to Cu 2+ , occupying three coordination sites of Cu(II) in a square-planar geometry. Binding of Cu + cations to guanine and adenine and in a noncomplementary DNA C−A base pair were explored in our previous studies.…”