Computational Study of Fluid Mechanical Disturbance Induced by Endovascular Stents

Seo, Taewon; Schachter, Levanto; Barakat, Abdul I.

doi:10.1007/s10439-005-2499-y

Cited by 128 publications

(119 citation statements)

References 40 publications

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“…Previously, it has been shown that local flow disturbances caused by stent struts result in low wall shear stress and re-circulating flows [22][23][24]. Local flow disturbances induced by stents eventually return to normal flows with large stent strut spacing corresponding to more rapid flow restoration [23].…”

Section: Effects Of Stent Strut Placement On Perforator Flowsmentioning

confidence: 99%

Flow diverter effect on cerebral aneurysm hemodynamics: an in vitro comparison of telescoping stents and the Pipeline

et al. 2013

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Section: Effects Of Stent Strut Placement On Perforator Flowsmentioning

confidence: 99%

Flow diverter effect on cerebral aneurysm hemodynamics: an in vitro comparison of telescoping stents and the Pipeline

et al. 2013

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“…These computational methods of analysis employ sophisticated numerical techniques, such as the finite element and finite volume methods, to obtain approximate numerical solutions to complex physical problems. To date, a large number of studies have carried out computational structural (CS) analyses 1,4,5,14,15,19,[25][26][27][28][29]37,44,53,54,57,59,[62][63][64]72,73,78,80,85,87,[90][91][92] and computational fluid dynamics (CFD) analyses 3,8,9,12,30,31,33,42,[47][48][49][50][51]65,66,69,[74][75][76]83,89 ...…”

Section: Introductionmentioning

confidence: 99%

Sequential Structural and Fluid Dynamics Analysis of Balloon-Expandable Coronary Stents: A Multivariable Statistical Analysis

Martín¹,

Boyle²

2015

Cardiovasc Eng Tech

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Abstract-Several clinical studies have identified a strong correlation between neointimal hyperplasia following coronary stent deployment and both stent-induced arterial injury and altered vessel hemodynamics. As such, the sequential structural and fluid dynamics analysis of balloon-expandable stent deployment should provide a comprehensive indication of stent performance. Despite this observation, very few numerical studies of balloon-expandable coronary stents have considered both the mechanical and hemodynamic impact of stent deployment. Furthermore, in the few studies that have considered both phenomena, only a small number of stents have been considered. In this study, a sequential structural and fluid dynamics analysis methodology was employed to compare both the mechanical and hemodynamic impact of six balloon-expandable coronary stents. To investigate the relationship between stent design and performance, several common stent design properties were then identified and the dependence between these properties and both the mechanical and hemodynamic variables of interest was evaluated using statistical measures of correlation. Following the completion of the numerical analyses, stent strut thickness was identified as the only common design property that demonstrated a strong dependence with either the mean equivalent stress predicted in the artery wall or the mean relative residence time predicted on the luminal surface of the artery. These results corroborate the findings of the large-scale ISAR-STEREO clinical studies and highlight the crucial role of strut thickness in coronary stent design. The sequential structural and fluid dynamics analysis methodology and the multivariable statistical treatment of the results described in this study should prove useful in the design of future balloon-expandable coronary stents.

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“…Although nonNewtonian behavior can be expected if the shear rate is less than 100 s −1 (Seo et al 25 ) this effect is not considered here; furthermore, the framework of this study is based on the work done by Charonko et al 13,14 in which the working fluid was a mixture of water and glycerine approximating the density and viscosity of human blood. Gravity is neglected in this problem as it has minor effect in comparison with pressure and viscous forces.…”

Section: Problem Formulationmentioning

confidence: 99%

Numerical investigation of pulsatile flow in endovascular stents

2013

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The flow in a plane channel with two idealized stents (one -shaped, the other X-shaped) is studied numerically. A periodic pressure gradient corresponding to one measured in the left anterior descending coronary artery was used to drive the flow. Two Reynolds numbers were examined, one (Re = 80) corresponding to resting conditions, the other (Re = 200) to exercise. The stents were implemented by an immersed boundary method. The formation and migration of vortices that had been observed experimentally was also seen here. In the previous studies, the compliance mismatch between stent and vessel was conjectured to be the reason for this phenomenon. However, in the present study we demonstrate that the vortices form despite the fact that the walls were rigid. Flow visualization and quantitative analysis lead us to conclude that this process is due to the stent wires that generate small localized recirculation regions that, when they interact with the near-wall flow reversal, result in the formation of these vortical structures. The recirculation regions grow and merge when the imposed waveform produces near-wall flow reversal, forming coherent quasi-spanwise vortices, that migrate away from the wall. The flow behavior due to the stents was compared with an unstented channel. The geometric characteristics of the -stent caused less deviation of the flow from an unstented channel than the X-stent. Investigating the role of advection and diffusion indicated that at Re = 80 advection has negligible contribution in the transport mechanism. Advection plays a role in the generation of streamwise vortices created for both stents at both Reynolds numbers. The effect of these vortices on the near-wall flow behavior is more significant for the -stent compared to the X-stent and at Re = 200 with respect to Re = 80. Finally, it was observed that increasing the Reynolds number leads to early vortex formation and the creation of the vortex in a stented channel is coincident with the near wall flow reversal in an unstented one. C 2013 AIP Publishing LLC. [http://dx

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Computational Study of Fluid Mechanical Disturbance Induced by Endovascular Stents

Cited by 128 publications

References 40 publications

Flow diverter effect on cerebral aneurysm hemodynamics: an in vitro comparison of telescoping stents and the Pipeline

Flow diverter effect on cerebral aneurysm hemodynamics: an in vitro comparison of telescoping stents and the Pipeline

Sequential Structural and Fluid Dynamics Analysis of Balloon-Expandable Coronary Stents: A Multivariable Statistical Analysis

Numerical investigation of pulsatile flow in endovascular stents

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