Computed Tomography Guided Transthoracic Fine Needle Aspiration Cytology in the Diagnosis of Sonographically Non-Approachable Intrathoracic Masses  A Study of 100 Cases

Introduction:Transthoracic guided fine needle aspiration cytology (FNAC) of clinically suspected lung tumors is an increasingly common procedure in diagnosis. Cytospin Smear and Cellblock preparations of available material are helpful in subtyping and confirming the diagnosis, and they can also be used for further studies, i.e., special stain and immunohistochemistry, etc.Aims and Objectives:This research was undertaken to study the technique of guided transthoracic lung FNAC of clinically suspected lung tumors and the establish role of FNAC smears, cytospin smears, and cellblocks in the detection and typing of neoplastic lung lesions and correlation.Materials and Methods:Guided FNAC was taken from 100 cases of clinically suspected lung tumor and FNAC smears, cytospin smears, and cellblocks of aspirated material were studied over a period of 2 years from September 2011 to September 2013.Results:The material adequacies were 80% in FNAC smears, 83% in cytospin smears, and 89% in cellblocks. Additional information supported by cytospin smear and cellblock was 3% and 9%, respectively. Architectural preservation was better in FNAC smears (85%) and cellblocks (73.03%) than that in cytospin smears (31.33%). Morphological preservation was better in FNAC smears (90%) and cellblocks (75.28%) than that in cytospin smears (14.46%). Diagnostic accuracy was increased in the cellblocks and cytospin smears.Conclusion:Cytospin smear was helpful when low cellular material was obtained, and the concomitant examination of cellblocks not only confirmed the diagnosis of malignancy but also helped in classifying the obtained material and allowed further study on the same.

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“…[456] Right-sided lesions (68) were common than left-sided lesions (32) which is accordance with the text and various other studies. [47]…”

Section: Discussionsupporting

confidence: 90%

Comparison of FNAC smears, cytospin smears, and cellblocks of transthoracic guided FNAC of suspected lung tumor: A study of 100 cases

Kshatriya

Santwani

2016

J Cytol

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“…Incidence of pleural lesions was found low in our study, which was comparable to other studies like Rangaswamy et al 16 and Kalhan S et al 10 . Lower specificity at 76% was recorded by Jayashankar et al 9 and at 84% by Basnet et al 13 Positive predictive value of our study was 100% which was similar to that of found in studies by Singh JP et al 12 and Sarkar RN et al 8 and negative predictive value was found to be 80% which was almost comparable to that found in studies done by Singh JP et al 12 (75%) and Basnet et al 13 (81%). Thus the validity parameters of our study showed that the cytological diagnosis was better than diagnosis made by only radiographic findings.…”

Section: Discussion:-supporting

confidence: 81%

Role and Accuracy of Computed Tomography Guided Fnac of Thoracic Lesion.

Tiwari¹,

Tewari²

2017

IJAR

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Background:-Computed tomography (CT)-guided fine needle aspiration cytology (FNAC) is regarded as a rapid, safe, and accurate diagnostic tool in examining thoracic mass lesions. Aims: To assess the role of CT-Guided FNAC in thoracic mass lesions, to analyze the results, and to compare the results with other studies. Materials and Methods: Fifty-five patients were studied over a period of one year (Sep 2011 to Oct 2012) for their age, sex, radiological findings and cytological diagnoses. Results: Sensitivity of CT guided FNAC in our study was found to be 92.5% and specificity as 100%. Diagnostic accuracy of CT guided FNAC was quite high at 94.2%. Positive Predictive Value was 100% and Negative Predictive Value, 80% Conclusion: CT guided trans-thoracic needle aspiration cytology using a 22 gauge spinal needle is a highly sensitive and specific technique with a good diagnostic accuracy and can be used safely as an outpatient procedure in the diagnosis of thoracic lesions.

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“…This is comparable with other published studies 5 & 15 When we analyzed the distribution of cases showed that majority were from lung parenchyma 37(67.27 %) followed by mediastinum 9(16.4%), thoracic vertebrae 3(5.5%), hilar 2(3.6%), pleural 2(3.6%) and paraspinal 2(3.6%) region. The predominance of pulmonary lesions over other thoracic masses has been seen in other studies done by Singh et al 5 (64.7%) and R. N. Sarjer et al 13 …”

Section: Discussion: Ct-guided Fine-needle Aspiration Cytology (Fnac)supporting

confidence: 57%

Role and Accuracy of Rapid on-Site Evaluation of Ct: Guided Fine Needle Aspiration Cytology of Throracic Lesions

Nandwani¹,

Krishnan²,

Chandrakar³

et al. 2014

jemds

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ABSTRACT:Computed tomography guided percutaneous transthoracic fine needle aspiration cytology (FNAC) of thoracic lesions is a widely accepted, simple, rapid, safe and accurate diagnostic tool of relatively low cost. OBJECTIVE: The aim of this study was to evaluate the diagnostic value of the noninvasive method of CT-guided needle aspiration cytology in the assessment of radiologically detected intra thoracic mass lesions, to analyze the results and to know the pathological spectrum of thoracic masses (both benign and malignant) along with the correlation of CT findings with cytopathological reports. SETTINGS AND DESIGN: We conducted an institution based prospective study on patients who presented with thoracic mass lesions in lungs, mediastinum, hilar lymph nodes, thoracic vertebrae, paraspinal soft tissues and pleura. Cytologic examination was performed on site after staining smears with the Hematoxylin and eosin method. It was possible to define the cytologic lineage in 94 percent of the cases and in 3 cases (5.4 percent) the material was insufficient for the cytologic diagnosis. The diagnostic accuracy of percutaneous transthoracic fine needle aspiration cytology was more than 90%.Out of 52 cases, 11 cases were non-neoplastic while 41 cases were neoplastic. Among the non-neoplastic lesions, specific diagnosis were obtained in 10 cases. The diagnostic sensitivity of malignancy was 92.5% and specificity was 100%, positive predictive value of 100 percent and negative of 80 percent. Male to female ratio was 2.9:1. Majority of cases was seen in 5 th to 6 th decade. The most common tumor was squamous cell carcinoma (44.82%) followed by adenocarcinoma (31.03%) Post procedural complications were few. CONCLUSIONS: This study showed that FNAC, under computed tomography guidance, is a simple, rapid, safe, sensitive and specific technique procedure with insignificant rate of complications for the diagnosis of thoracic lesions. It can be used as a first line of investigation and also helps in deciding on appropriate management.

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Computed Tomography Guided Transthoracic Fine Needle Aspiration Cytology in the Diagnosis of Sonographically Non-Approachable Intrathoracic Masses A Study of 100 Cases

Cited by 6 publications

References 9 publications

Comparison of FNAC smears, cytospin smears, and cellblocks of transthoracic guided FNAC of suspected lung tumor: A study of 100 cases

Comparison of FNAC smears, cytospin smears, and cellblocks of transthoracic guided FNAC of suspected lung tumor: A study of 100 cases

Role and Accuracy of Computed Tomography Guided Fnac of Thoracic Lesion.

Role and Accuracy of Rapid on-Site Evaluation of Ct: Guided Fine Needle Aspiration Cytology of Throracic Lesions

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Computed Tomography Guided Transthoracic Fine Needle Aspiration Cytology in the Diagnosis of Sonographically Non-Approachable Intrathoracic Masses  A Study of 100 Cases

Cited by 6 publications

References 9 publications

Comparison of FNAC smears, cytospin smears, and cellblocks of transthoracic guided FNAC of suspected lung tumor: A study of 100 cases

Comparison of FNAC smears, cytospin smears, and cellblocks of transthoracic guided FNAC of suspected lung tumor: A study of 100 cases

Role and Accuracy of Computed Tomography Guided Fnac of Thoracic Lesion.

Role and Accuracy of Rapid on-Site Evaluation of Ct: Guided Fine Needle Aspiration Cytology of Throracic Lesions

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Computed Tomography Guided Transthoracic Fine Needle Aspiration Cytology in the Diagnosis of Sonographically Non-Approachable Intrathoracic Masses A Study of 100 Cases