Computed tomography of primary malignant fibrohistiocytoma of the lung

Ismailer, Ida; Khan, Arfa; Leonidas, John C.; Wind, Edward S.; Herman, Peter C.

doi:10.1016/0730-4862(87)90027-8

Cited by 12 publications

(4 citation statements)

References 6 publications

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“…In our case was compatible with the literature. Pediatric cases have been reported as age range [4]. Male was predominance, but some literature reported female frequently occurred [3].…”

Section: Discussionmentioning

confidence: 99%

Successful Management of a Recurrent Primary Malignant Fibrous Histiocytoma of the Lung: Report of a Case

Jeon

Park

2012

Korean J Thorac Cardiovasc Surg

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We describe herein an extremely rare case of a recurrent primary pulmonary malignant fibrous histiocytoma 3 months after operation that occurred in a 55-year-old man who was treated with chemotherapy and radiotherapy successfully. Until now, 36 months later, the patient has shown no evidence of tumor recurrence. The clinical, radiographic, and pathologic features are reported here together with a brief review of the literature.

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“…In our case was compatible with the literature. Pediatric cases have been reported as age range [4]. Male was predominance, but some literature reported female frequently occurred [3].…”

Section: Discussionmentioning

confidence: 99%

Successful Management of a Recurrent Primary Malignant Fibrous Histiocytoma of the Lung: Report of a Case

Jeon

Park

2012

Korean J Thorac Cardiovasc Surg

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“…Over half of the tumors involved the lower lobes, and 70% were described as peripheral [2,3]. Although calcification has not been reported in adults, lsmailer et al [6] showed punctate calcifications with CT in a single pediatric patient. Twenty percent of patients have had ipsilateral pleural effusion, including a patient who had a right pleural effusion and obliteration of the right border of the heart [2,3].…”

Section: Case Reportmentioning

confidence: 99%

Malignant fibrous histiocytoma of the lung in a patient with a history of asbestos exposure.

Reifsnyder

Smith

Mullhollan

et al. 1990

American Journal of Roentgenology

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“…The immunohistochemical characteristics are as follows: α1-antitrypsin and α1-antichymotrypsin, vimentin (+), S-100 protein (-), and myosin (-) ( 2 ). Because the growth of PMFHL is a centrifugal spherical enlargement phenomenon, the surrounding normal tissue is compressed and changed in layers, forming a relatively tight “compression zone”, and a tissue reaction phenomenon occurs around the “compression zone” to form a pseudocapsule ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

EML4-ALK rearrangement in primary malignant fibrous histiocytoma of the lung treated with alectinib: A case report

2022

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Primary malignant fibrous histiocytoma of the lung (PMFHL) is extremely rare. It is more common in the right lung and has no specific symptoms. Lymph node metastasis is rare, but hematogenous metastasis is more common. The common metastatic sites are the brain and bone. In this study, a 59-year-old male patient was diagnosed with PMFHL with brain metastasis due to persistent cough and blood in the sputum for the past week. Genetic testing revealed EML4-ALK gene rearrangement (fusion). We first used alectinib in a patient with advanced PMFHL with EML4-ALK gene rearrangement (fusion) accompanied by brain metastasis. The treatment was effective and successfully delayed the development of the disease. Satisfactory results were observed, with an overall survival time of 19 months. Therefore, genetic testing in PMFHL and the choice of treatment plan are important. Local treatment methods, including surgery and radiotherapy, are important when the disease is less advanced. Multidisciplinary discussion is recommended for the best prognosis.

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Computed tomography of primary malignant fibrohistiocytoma of the lung

Cited by 12 publications

References 6 publications

Successful Management of a Recurrent Primary Malignant Fibrous Histiocytoma of the Lung: Report of a Case

Successful Management of a Recurrent Primary Malignant Fibrous Histiocytoma of the Lung: Report of a Case

Malignant fibrous histiocytoma of the lung in a patient with a history of asbestos exposure.

EML4-ALK rearrangement in primary malignant fibrous histiocytoma of the lung treated with alectinib: A case report

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