Computed Tomography of Renal Lymphoma with Ultrasound Correlation

Extensive Extranodal Involvement of Rare Sites in Non Hodgkin’s Lymphoma Detected on 18F- FDG PET-CT: A Case Report

“…Interestingly secondary to bilateral testicular involvement, the more pronounced along the medial wall with adjacent small ileo-caecal node (d) and well marginated soft tissue attenuation lesions in left paraaortic (arrow) (e) and precaval location (arrow) (f) consistent with lymphomatous ileal involvement and nodal deposits Fig. 2 Maximum intensity projection images of PET-CT scan shows multifocal increased 18 F-FDG uptake in the mediastinum (arrow head), gastrointestinal tract (outline arrow and connected arrow), kidneys (thin black arrow) and scrotal region (thick black arrow) patient developed bilateral testicular vein thrombosis. The patient is now being planned for second line chemotherapy.…”

“…Serum lactate dehydogenase levels were elevated (630 IU/L). The patient was thereafter referred to the nuclear medicine department for staging 18 F-FDG PET-CT. PET-CT showed abnormally increased 18 F-FDG uptake in right and left atria, bilateral renal cortices, left testis, terminal ileum, ileo-caecal junction, and in multiple mesenteric and retroperitoneal lymph nodes (Figs. 2 and 3).…”

“…The patient underwent combination chemotherapy with cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone along with rituximab (R-CHOP regimen). 18 F-FDG PET-CT was repeated after four cycles of chemotherapy to assess treatment response. It showed progression of disease at all sites including heart, kidneys and testes (Fig.…”

“…Malignancies of lymphoid cells may present as leukemia (i.e., primary involvement of bone marrow and blood), or as lymphoma (i.e., solid tumors of the immune system) [1]. The role of 18 F-fluorodeoxyglucose positron emission tomography ( 18 F-FDG PET) and PET-CT (positron emission tomography-computed tomography) has been extensively evaluated in the management of Hodgkin's disease (HD) and non Hodgkin's lymphoma (NHL) [2][3][4][5][6][7]. PET-CT has shown significant improvement in staging and restaging when compared to conventional imaging modalities such as contrast-enhanced computed tomography (CECT) [4][5][6][7].…”

“…PET-CT has shown significant improvement in staging and restaging when compared to conventional imaging modalities such as contrast-enhanced computed tomography (CECT) [4][5][6][7]. The role of 18 F-FDG PET-CT in detection, staging and restaging of patients with extranodal involvement in NHL has also been reported in the literature [2,3]. Multiple isolated cases with extranodal involvement of NHL, detected on PET-CT, have been previously reported [8][9][10][11].…”