Computer-assisted lung nodule volumetry from multi-detector row CT: Influence of image reconstruction parameters

Honda, Osamu; Sumikawa, Hiromitsu; Johkoh, Takeshi; Tomiyama, Noriyuki; Mihara, Naoki; Tsubamoto, Mitsuko; Natsag, Javzandulam; Hamada, Seiki; Nakamura, Hajime

doi:10.1016/j.ejrad.2006.11.017

Cited by 35 publications

(32 citation statements)

References 22 publications

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“…Volumetric software-derived measurements demonstrate less variation [55,56], although this can still occur for a variety of reasons [57][58][59][60][61]. Segmentation of a nodule attached to the pleura or vessels is also difficult with current software packages.…”

Section: What Factors Influence Variability In Nodule Measurement?mentioning

confidence: 99%

European and North American lung cancer screening experience and implications for pulmonary nodule management

Nair

Hansell

2011

Eur Radiol

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The potential for low dose computed tomography (LDCT) to act as an effective tool in screening for lung cancer is currently the subject of several randomised control trials. It has recently been given prominence by interim results released by the North American National Lung Screening Trial (NLST). Several other trials assessing LDCT as a screening tool are currently underway in Europe, and are due to report their final results in the next few years. These include the NELSON, DLSCT, DANTE, ITALUNG, MILD and LUSI trials. Although slow to instigate a trial of its own, the UK Lung Screen (UKLS) trial will shortly commence. The knowledge gained from the newer trials has mostly reinforced and refined previous concepts that have formed the basis of existing nodule management guidelines. This article takes the opportunity to summarise the main aspects and initial results of the trials presently underway, assess the status of current collaborative efforts and the scope for future collaboration, and analyse observations from these studies that may usefully inform the management of the indeterminate pulmonary nodule. Key Points • Low dose CT screening for lung cancer is promising. • The effect of LDCT screening on mortality is still uncertain. • Several European randomised controlled trials for LDCT are underway. • The trials vary in methodology but most compare LDCT to no screening. • Preliminary results have reinforced existing nodule management concepts.

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Section: What Factors Influence Variability In Nodule Measurement?mentioning

confidence: 99%

European and North American lung cancer screening experience and implications for pulmonary nodule management

Nair

Hansell

2011

Eur Radiol

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“…There are several technical factors affecting nodule volume estimation, such as section thickness [40,68,69,[86][87][88][89] and overlapping [90,91], pitch mode [92], reconstruction algorithm [86,[89][90][91][93][94][95] and intravenous contrast medium injection [95][96][97], as summarised in table 2. In addition, major technical concerns exist regarding nodule volumetry during follow-up.…”

Section: Factors Influencing Nodule Measurement Variationsmentioning

confidence: 99%

Lung nodules: size still matters

et al. 2017

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The incidence of indeterminate pulmonary nodules has risen constantly over the past few years. Determination of lung nodule malignancy is pivotal, because the early diagnosis of lung cancer could lead to a definitive intervention. According to the current international guidelines, size and growth rate represent the main indicators to determine the nature of a pulmonary nodule. However, there are some limitations in evaluating and characterising nodules when only their dimensions are taken into account. There is no single method for measuring nodules, and intrinsic errors, which can determine variations in nodule measurement and in growth assessment, do exist when performing measurements either manually or with automated or semi-automated methods. When considering subsolid nodules the presence and size of a solid component is the major determinant of malignancy and nodule management, as reported in the latest guidelines. Nevertheless, other nodule morphological characteristics have been associated with an increased risk of malignancy. In addition, the clinical context should not be overlooked in determining the probability of malignancy. Predictive models have been proposed as a potential means to overcome the limitations of a sized-based assessment of the malignancy risk for indeterminate pulmonary nodules.

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“…These computer-aided methods are preferred to two-dimensional measurements made by hand or using electronic callipers because of the limitations deriving from the intra-and interobserver variability (reproducibility) of these techniques [1]. However, several studies have found that the results of computer-aided volume measurements may be influenced, at times even heavily, by a variety of factors, including the type of computed tomography (CT) scanner [2], image acquisition and reconstruction parameters [3,4] and type of software used [5]. Following an update of the software used on the CT image reconstruction workstation of our centre, we assessed whether there is a variability of results capable of affecting assessment of pulmonary nodule growth between different versions of the same volumetric software.…”

Section: Introductionmentioning

confidence: 98%

Three-dimensional analysis of pulmonary nodules: variability of semiautomated volume measurements between different versions of the same software

et al. 2010

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Computer-assisted lung nodule volumetry from multi-detector row CT: Influence of image reconstruction parameters

Cited by 35 publications

References 22 publications

European and North American lung cancer screening experience and implications for pulmonary nodule management

European and North American lung cancer screening experience and implications for pulmonary nodule management

Lung nodules: size still matters

Three-dimensional analysis of pulmonary nodules: variability of semiautomated volume measurements between different versions of the same software

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