1986
DOI: 10.1016/0270-0255(86)90129-6
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Computerized epidemiological model of typhoid fever with age structure and its use in the planning and evaluation of antityphoid immunization and sanitation programmes

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Cited by 32 publications
(47 citation statements)
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“…It is generally assumed that the risk of transmission is similar between acutely infectious individuals and chronic carriers. Therefore, determining the prevalence of excreters, including asymptomatic carriers, in any population is important for modeling transmission dynamics and the potential impact of vaccination for this disease [44,45]. The role of S. Typhi carriers in the persistence of typhoid fever in endemic regions has been observed in parts of Chile [46] and Vietnam [47], and the impact of carriers on incident typhoid fever cases is consistent with output from stochastic modeling of typhoid fever transmission [48].…”
Section: Discussionmentioning
confidence: 66%
“…It is generally assumed that the risk of transmission is similar between acutely infectious individuals and chronic carriers. Therefore, determining the prevalence of excreters, including asymptomatic carriers, in any population is important for modeling transmission dynamics and the potential impact of vaccination for this disease [44,45]. The role of S. Typhi carriers in the persistence of typhoid fever in endemic regions has been observed in parts of Chile [46] and Vietnam [47], and the impact of carriers on incident typhoid fever cases is consistent with output from stochastic modeling of typhoid fever transmission [48].…”
Section: Discussionmentioning
confidence: 66%
“…Typhoid fever remains one of the leading causes of morbidity and mortality in most of the developing countries with an incidence rate of >100/100,000 population in most South East Asian countries including India [14]. It has been suggested that only 20% of all those infected by S. Typhi would develop classical disease whereas 80% remain asymptomatic [15,16]. In India, approximately 15 million people acquire clinical/sub clinical infection each year and about 3 %( 450,000) of them might be added to the pool of chronic carriers.…”
Section: Introductionmentioning
confidence: 99%
“…It has been suggested that only 20% of all those infected by S. typhi would develop classical disease whereas 80% remain asymptomatic [11,12]. In India, approximately 15 million people acquire clinical/sub clinical infection each year and only 3% (450,000) of them might be added to the pool of chronic carriers.…”
Section: Discussionmentioning
confidence: 99%