Computerized planimetry versus clinical assessment for the measurement of cervical ectopia

Morrison, Charles; Bright, Patricia; Blumenthal, Paul D.; Yacobson, Irina; Kwok, Cynthia; Zdenek, Susan; Pan, Zhiying

doi:10.1067/mob.2001.113125

Cited by 9 publications

(7 citation statements)

References 21 publications

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“…Using computerized planimetry to measure cervical ectopia has been suggested [21]. In our study, there was complete agreement between the clinicians in the degree of ectopy during the menstrual cycle using standard colored disks.…”

Section: Discussionsupporting

confidence: 64%

Colposcopically Observed Vascular Changes in the Cervix in Relation to the Hormonal Levels and Menstrual Cycle

Joshi¹,

Das²,

Thakar³

et al. 2008

Journal of Lower Genital Tract Disease

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Objective We assessed colposcopically observed vascular changes occurring in the cervix in relation to cyclical hormonal variation in healthy women. Materials and Methods Thirty women with regular menstrual cycles and willing to remain sexually abstinent during a menstrual cycle were enrolled. Colposcopy was performed during the peak of the estrogen and progesterone levels. Results The mean (±SD) diameter of the largest visible blood vessel differed significantly between the estrogenic phase (0.38 ± 0.14 mm) as compared with the progestogenic phase (0.47 ± 0.12 mm; p < .01). The blood vessels were more prominent and dense and had a well-defined outline during the progestogenic phase than the estrogenic phase; however, these differences were not statistically significant. There was borderline increase in the interleukin 8 level during the estrogenic phase. Conclusions Physiological changes of increased vascularity of the cervix observed colposcopically during the progestogenic phase are normal. If such changes do not correspond to the menstrual cycle phase in women using vaginal microbicides in early-phase clinical trials, presence of inflammatory markers should be evaluated. Elevated interleukin 8 during the estrogenic phase needs further evaluation.

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Section: Discussionsupporting

confidence: 64%

Colposcopically Observed Vascular Changes in the Cervix in Relation to the Hormonal Levels and Menstrual Cycle

Joshi¹,

Das²,

Thakar³

et al. 2008

Journal of Lower Genital Tract Disease

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“…Likewise, we used a sensitive and highly reliable measure of cervical ectopy. 17 Finally, we enrolled a diverse population of women seeking reproductive health services (various ages, ethnic groups, and so on). This is important because the dynamics of cervical infections could differ by population groups.…”

Section: Discussionmentioning

confidence: 99%

“…17 Briefly, after application of 4% acetic acid to the cervix, the clinician placed a vinyl dot of a known diameter (0.476 cm) on the face of the cervix. She then took 3 cervical photographs using a 35-mm Dental Eye II Camera with a ring flash (Yashica Inc., Somerset, NJ) before removing the vinyl dot.…”

Section: Study Population and Proceduresmentioning

confidence: 99%

Hormonal Contraceptive Use, Cervical Ectopy, and the Acquisition of Cervical Infections

Morrison¹,

Bright²,

Wong³

et al. 2004

Sexually Transmitted Diseases

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100

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“…Our ectopy measurement methods have been described in detail previously [25]. A clinician applied 4% acetic acid to the cervix.…”

Section: Methodsmentioning

confidence: 99%

“…The absolute area of ectopy was calibrated by comparing the outlined area of ectopy against the diameter of the vinyl dot. The independent rater also calculated the proportion of the cervix covered by ectopy [25]. …”

Section: Methodsmentioning

confidence: 99%

Hormonal contraception and area of cervical ectopy: a longitudinal assessment

et al. 2011

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Background The effect of combined oral contraceptives (COCs) and depot-medroxyprogesterone acetate (DMPA) on the area of cervical ectopy is not well understood. Study Design From 1996–1999, we recruited women not using hormonal contraception from two family planning centers in Baltimore, Maryland. Upon study entry and 3, 6 and 12 months after the initial visit, participants were interviewed and received visual cervical examinations with photography. Ectopy was measured from digitized photographs and was analyzed both continuously and categorically (small (≤0.48 cm2) vs. large (>0.48 cm2)). Results Of 1,003 enrolled women, 802 returned for at least one follow-up visit. At 12 months, the numbers of women using COCs, DMPA, or no hormonal method at least 50% of the time since the prior visit were 230, 76, and 229 respectively. After multivariable adjustment, COC use (vs. no hormonal use) was associated with large area of ectopy (odds ratio (OR): 1.8, 95% confidence interval (CI) 1.0 to 3.3). No significant relationship was observed between DMPA and large area of ectopy (OR: 0.5, 95% CI: 0.2–1.3). The incidence of large area of ectopy by contraceptive exposure (COC, DMPA, or no hormonal method) was 17.4 (CI: 11.8, 24.6), 10.9 (CI: 4.4, 22.4) and 4.6 (CI: 2.2, 8.4) per 100 woman-years, respectively. Conclusions Use of COCs, but not DMPA, was associated with large area of cervical ectopy. Area of ectopy at baseline was the strongest predictor of area of ectopy at follow-up.

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Computerized planimetry versus clinical assessment for the measurement of cervical ectopia

Cited by 9 publications

References 21 publications

Colposcopically Observed Vascular Changes in the Cervix in Relation to the Hormonal Levels and Menstrual Cycle

Colposcopically Observed Vascular Changes in the Cervix in Relation to the Hormonal Levels and Menstrual Cycle

Hormonal Contraceptive Use, Cervical Ectopy, and the Acquisition of Cervical Infections

Hormonal contraception and area of cervical ectopy: a longitudinal assessment

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