“…The RCT was rated as good quality, the case-control study was rated as poor quality, and the cross-sectional studies were generally of reasonable quality (see Appendix S3 in the Supporting Information online ). Tissue samples comprised bone (n = 4) (ie, rib, vertebrae, femur), 29 , 111 , 116 , 118 muscle (n = 4) (ie, diaphragm, abdominal wall, and gluteal area), 27 , 28 , 30 , 43 organs (n = 23) (ie, aorta, brain, eye, glands, gastrointestinal tract, heart, kidney, liver, lung, and skin), 28 , 40–46 , 108–115 , 117 , 119–122 and whole blood (n = 1). 71 Details of these studies are provided in Table S4 in the Supporting Information online , and the forest plot, including data from all ages, is presented in Figure S9 in the Supporting Information online .…”