Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)

Abstract

The functionalization of smart polymers is opening a new perspective in catalysis, drug carriers and biosensors, due to the fact that they can modulate the response regarding conventional devices. This smart response could be affected by the presence of organometallic complexes in terms of interactions which could affect the physical chemical properties. In this sense, the thermoresponsive behavior of copolymers based on N-isopropylacrylamide (NIPAM) could be affected due to the presence of hydrophobic groups and concentration effect. In this work, the functionalization of a copolymer based on NIPAM and dopamine methacrylamide with different amounts of bis(cyclopentadienyl)titanium (IV) dichloride was carried out. The resulting materials were characterized, showing a clear idea about the mechanism of functionalization through FTIR spectroscopy. The thermoresponsive behavior was also studied for various polymeric solutions in water by UV–vis spectroscopy and calorimetry. The hydrophobic interactions promoted by the organometallic complex could affect the transition associated with the lower critical solution temperature (LCST), specifically, the segments composed by pure NIPAM. That fact would explain the reduction of the width of the LCST-transition, contrary to what could be expected. In addition, the hydrophobicity was tested by the contact angle and also DNA interactions.

Fumaric Acid Production by R. arrhizus NRRL 1526 Using Apple Pomace Enzymatic Hydrolysates: Kinetic Modelling

“…Green chemistry and engineering are sustainability tools that have experienced a great growth in recent years for the aforementioned reasons [4]. Additionally, biorefineries appear as an integrated and integral process strategy based on the petrochemical industry but focusing on the modification of biomass as the source for an almost unlimited array of products, biomass being a global term encompassing all renewable and sustainable raw materials created in the biosphere, that is, by living beings [5].…”

Water-Soluble and -Insoluble Polymers and Biopolymers for Biomedical, Environmental, and Biological Applications

“…Moral-Zamorano et al [3] synthesized copolymers based on N-isopropylacrylamide (NIPAM) and dopamine methacrylamide (DMA)-called NIDO-and further functionalized them with the organometallic complex bis(cyclopentadienyl)titanium (IV) dichloride. This work is in a line of research investigations on NIDO and related polymers with respect to its physicochemical behavior [4][5][6][7][8][9] and for various applications, especially in the biomedical field [10].…”

“…This work is in a line of research investigations on NIDO and related polymers with respect to its physicochemical behavior [4][5][6][7][8][9] and for various applications, especially in the biomedical field [10]. The paper of Moral-Zamorano et al [3] determined the effect of the loading of the organometallic complex on thermoresponsivity. While increasing the loading of the organometallic complex decreases the lower critical solution temperature somewhat, it leads to a very sharp change in the behavior, which only spans a transition temperature range of ca.…”