Concentration of antioxidant compounds and lipid peroxidation in the liver and white muscle of hake (Merluccius merluccius L.) in the Adriatic sea

Ognjanovic, I Branka; Djordjević, Nataša; Perendija, R Branka; Despotović, Svetlana G.; Žikić, Radoslav V.; Štajn, Andraš Š.; Saicic, S Zorica

doi:10.2298/abs0804601o

Cited by 8 publications

(1 citation statement)

References 16 publications

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“…Changes in abiotic factors (salinity, dissolved oxygen, temperature etc.) as a consequences of change in seasons may therefore influence normal metabolic activities of organisms and the induction of oxidation stress as a consequence of increased generation of Reactive Oxygen Species (ROS) (Van der Oost et al, 2003;Ognjanovic et al, 2008;Malanga et al, 2009). The ROS can be highly toxic to aquatic organisms including molluscs after resulting in oxidation of lipid in membranes, protein and nucleic acids, polysaccharides and inhibition of vital enzymes (Mates, 2000;De Almeida et al, 2007;Tripathi et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

Anti-reproductive Activity of Chlorophyllin on Fresh Water Snail Lymnaea acuminata

Singh¹,

Sing²

2015

Research J. of Parasitology

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The effects of Sub-lethal treatments (20 and 60% of 24 h LC 50 ) of chlorophyllin on the reproduction and development of Lymnaea acuminata has been studied. There was a significant decrease in the fecundity, hatchability and survival of the young snails. Treatment with 60% of 24 h LC 50 of chlorophyllin caused minimum fecundity (57 eggs/20 snails, 48 h) in summer (sunlight). After 48 h no egg laying and hatching was noted in snails exposed to 60% of 24 h LC 50 of chlorophyllin in both winter (sunlight) as well as in summer (sunlight). Development could not proceed beyond the veliger stage due to the death of the embryo. The developmental arrest was noticed in many egg strings leading to the high rate of mortality and there by reduction in hatchability of the eggs. Growth rate of survived snails was also very slow. This present study clearly shows that the efficacy of chlorophyllin gives significant control of reproduction of the snails even at sub-lethal exposure. The use of the natural products would have an added advantage against aquatic snails as it would be non toxic to the non target animals and less hazardous to the environment.

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Section: Discussionmentioning

confidence: 99%

Anti-reproductive Activity of Chlorophyllin on Fresh Water Snail Lymnaea acuminata

Singh¹,

Sing²

2015

Research J. of Parasitology

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Chronic Effects of Realistic Concentrations of Non-essential and Essential Metals (Lead and Zinc) on Oxidative Stress Biomarkers of the Mosquitofish, Gambusia holbrooki

Nunes

Caldeira

Pereira

et al. 2015

Arch Environ Contam Toxicol

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Metallic contamination is widespread, particularly in areas impacted by human activities. Human activities result in high loads of metals being discarded into the aquatic compartment, reinforcing the need to evaluate their toxic effects especially on exposed fish. The purpose of this study was to determine the toxic response (namely, antioxidant levels and lipoperoxidative damage) in both liver and gills of the freshwater fish species Gambusia holbrooki, exposed to lead and zinc. Fish were exposed for 28 days (chronic exposure) to ecologically relevant concentrations of the selected compounds. The following oxidative stress/damage biomarkers were evaluated: glutathione-S-transferases (GSTs), glutathione reductase (GR), and thiobarbituric acid reactive substances (TBARS). The results indicate that lead caused a significant oxidative response, with significant increase of the enzymatic antioxidant defense (GSTs activity in hepatic tissue, and GR activity in branchial tissue) of exposed organisms. On the other hand, zinc caused a significant inhibition of G. holbrooki hepatic GR, a biological response that may be related to the antioxidant activity exhibited by this metal. The obtained results are of high importance, especially if one considers that the obtained toxic responses occurred at low, albeit ecologically relevant, levels of exposure.

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Glutathione, glutathione S-transferase, and glutathione conjugates, complementary markers of oxidative stress in aquatic biota

Hellou

Ross

Moon

2012

Environ Sci Pollut Res

167

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Contaminants are ubiquitous in the environment and their impacts are of increasing concern due to human population expansion and the generation of deleterious effects in aquatic species. Oxidative stress can result from the presence of persistent organic pollutants, metals, pesticides, toxins, pharmaceuticals, and nanomaterials, as well as changes in temperature or oxygen in water, the examined species, with differences in age, sex, or reproductive cycle of an individual. The antioxidant role of glutathione (GSH), accompanied by the formation of its disulfide dimer, GSSG, and metabolites in response to chemical stress, are highlighted in this review along with, to some extent, that of glutathione S-transferase (GST). The available literature concerning the use and analysis of these markers will be discussed, focusing on studies of aquatic organisms. The inclusion of GST within the suite of biomarkers used to assess the effects of xenobiotics is recommended to complement that of lipid peroxidation and mixed function oxygenation. Combining the analysis of GSH, GSSG, and conjugates would be beneficial in pinpointing the role of contaminants within the plethora of causes that could lead to the toxic effects of reactive oxygen species.

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Concentration of antioxidant compounds and lipid peroxidation in the liver and white muscle of hake (Merluccius merluccius L.) in the Adriatic sea

Cited by 8 publications

References 16 publications

Anti-reproductive Activity of Chlorophyllin on Fresh Water Snail Lymnaea acuminata

Anti-reproductive Activity of Chlorophyllin on Fresh Water Snail Lymnaea acuminata

Chronic Effects of Realistic Concentrations of Non-essential and Essential Metals (Lead and Zinc) on Oxidative Stress Biomarkers of the Mosquitofish, Gambusia holbrooki

Glutathione, glutathione S-transferase, and glutathione conjugates, complementary markers of oxidative stress in aquatic biota

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