Concentration of Copper, Iron, Zinc, Cadmium, Lead, and Nickel in Boar Semen and Relation to the Spermatozoa Quality

Massányi, Peter; Trandžík, J.; Naď, P.; Korénekova, Beáta; Skalická, M.; Toman, R.; Lukáč, Norbert; Strapák, Peter; Halo, Marko; Turcan, Jan

doi:10.1081/ese-120024453

Cited by 34 publications

(18 citation statements)

References 15 publications

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“…In our previous studies we described various lead concentrations in semen affecting the quality of spermatozoa. [25,26] Lead administration reflects in the appreciable decline in fertility status. In cell kinetic studies, significant declines in various cell populations, spermatids and mature spermatozoa were detected.…”

Section: Discussionmentioning

confidence: 99%

Lead-induced alterations in rat kidneys and testesin vivo

Massányi

Lukáč

Makarevich³

et al. 2007

Journal of Environmental Science and Health, Part A

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The purpose of this study was to assess the effects of lead administration on the kidney and testicular structure of adult rats. Rats received lead (PbNO(3)) in single intraperitoneal dose 50 mg/kg (group A), 25 mg/kg (group B) and 12.5 mg (group C) per kilogram of body weight and were killed 48 h following lead administration. After the preparation of histological samples the results were compared with control. After the lead administration dilated Bowman's capsules and blood vessels in interstitium of kidney with evident hemorrhagic alterations were noted. Quantitative analysis determined increased relative volume of interstitium and tubules. Also, the diameter of renal corpuscules, diameter of glomeruli and diameter of Bowman's capsule were significantly increased, especially in group A, with the highest lead concentration. In testes, dilatation of blood capillaries in interstitium, undulation of basal membrane and occurrence of empty spaces in seminiferous epithelium were detected. An apoptosis assay confirmed increased incidence of apoptosis in the spermatogenetic cells after the lead administration. Also further morphometric analysis showed significant differences in evaluated parameters between control and treated groups. The number of cell nuclei was decreased in lead-treated groups, which is concerned with the occurrence of empty spaces as well as with the higher apoptosis incidence in germinal epithelium. This study reports a negative effect of lead on the structure and function of kidney and testes.

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Section: Discussionmentioning

confidence: 99%

Lead-induced alterations in rat kidneys and testesin vivo

Massányi

Lukáč

Makarevich³

et al. 2007

Journal of Environmental Science and Health, Part A

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“…Min-eral supplementation in the diet is almost ubiquitous in lactating ewes, but is much less routine in non lactating herds. Moreover, the trace mineral status of animals depends not only on dietary allowance, but also on the efficiency of digestion and storage, with both likely to be affected by interactions with other food constituents (Massanyi et al 2003a). Hence, trace elements deficiencies are often suspected by veterinary surgeons in low performance herds, and when assessed, a deficient status is considered as the likely cause of disorders.…”

Section: Discussionmentioning

confidence: 99%

Hematology and blood microelements of sheep in south Bohemia

Šoch¹,

Brouček

Srejberova³

2010

Biologia

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The efficiency of sheep is dependent on their health and well-being. The blood markers can be critical for improving of the physiological, nutritional and pathological status of sheep organism. The aim of this study was to test the hypotheses that the red and white blood cells and copper (Cu) and zinc (Zn) plasma contents are impacted by altitude and season. The ewes were kept at three farms. Blood samples were divided according to factors of altitude (550 m Spring values of haemoglobin and haematocrit were lower than fall values. The highest count of leucocytes was recorded at the altitude 950 m (9.57 G L −1 ), higher counts were contained in spring (P < 0.001). The lowest percentage of eosinophiles was found at the altitude of 800 m (5.81%) and the highest at the altitude of 550 m (9.26%) (P < 0.01). Phagocytose activities were the highest at the altitude of 950 m (95.07%) and the lowest at the altitude of 550 m (85.04%) (P < 0.001). Phagocytose activities were higher in fall than in spring. The highest Cu concentration was found at the altitude of 550 m and the lowest at the altitude of 800 m (17.04 µmol L −1 vs. 14.37 µmol L −1 ). Zn levels were higher at altitudes of 950 m and 800 m than at the altitude of 550 m (17.81 µmol L −1 , 17.00 µmol L −1 vs. 14.77 µmol L −1 ). We concluded that hematological markers and trace mineral content in grazed sheep may be impacted by altitude and season.

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“…Copper is involved in biochemical reactions even at the cellular level, especially in the oxidation-reduction processes. [12][13][14][15][16][17] Generally, studies reporting effects of various metals on spermatogenesis in nontoxic environment that may influence individual susceptibility to adverse effects are lacking. Zinc deficiency results in disorders of testes development and course of spermatogenesis.…”

Section: Introductionmentioning

confidence: 99%

Concentration of Copper, Iron, Zinc, Cadmium, Lead, and Nickel in Bull and Ram Semen and Relation to the Occurrence of Pathological Spermatozoa

Mass�nyi¹,

Trandzik²,

Nad³

et al. 2004

J Environ Sci Health A Tox Hazard Subst Environ Eng

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In this study the concentration of copper, iron, zinc, cadmium, lead, and nickel in bull and ram semen and relation of these metals to spermatozoa morphology was investigated. Analysis by atomic absorption spectrophotometry showed that copper concentration was significantly higher (p<0.0001) in ram semen in comparison with bull semen. The zinc concentration was higher in bull semen in comparison with ram semen. The iron and cadmium concentrations in the semen were similar. Higher concentration of lead was found in ram semen. Higher levels of nickel were found in ram semen in comparison with bulls. In bull semen 11.79+/-4.88% of pathological spermatozoa was found. Higher occurrence of pathological spermatozoa was in ram semen (17.17+/-3.76) in comparison with the semen of bulls. Separated tail, tail torso, and knob twisted tail were the most frequent forms of pathological spermatozoa in both species. Correlation analysis in bulls showed high positive relation between iron and zinc (r = 0.72), nickel and separated tail (r = 0.76), separated tail and tail torso (r = 0.71), tail torso and total number of pathological spermatozoa (r=0.72), and between tail ball and total number of pathological spermatozoa (r = 0.78). In rams high positive correlation between cadmium and lead (r=0.98), nickel and separated tail (r=0.77), separated tail and total number of pathological spermatozoa (r=0.69), knob twisted tail and retention of cytoplasmic drop (r=0.78), and between knob twisted tail and other pathological spermatozoa (r = 0.71) was found. High negative correlation in ram semen was observed between copper and nickel (r=0.71), copper and separated tail (r=0.70), and between iron and tail torso (r=0.67). The results suggest that the studied metals have a direct effect on spermatozoa quality.

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Concentration of Copper, Iron, Zinc, Cadmium, Lead, and Nickel in Boar Semen and Relation to the Spermatozoa Quality

Cited by 34 publications

References 15 publications

Lead-induced alterations in rat kidneys and testesin vivo

Lead-induced alterations in rat kidneys and testesin vivo

Hematology and blood microelements of sheep in south Bohemia

Concentration of Copper, Iron, Zinc, Cadmium, Lead, and Nickel in Bull and Ram Semen and Relation to the Occurrence of Pathological Spermatozoa

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