Concurrent presence of secretory carcinoma and Warthin’s tumor in ipsilateral parotid gland

Kaleem, Arshad; Patel, Neel; Alzahrani, Shadi; Hatoum, Hisham; Tursun, Ramzey

doi:10.1016/j.oraloncology.2020.104691

Cited by 5 publications

(6 citation statements)

References 17 publications

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“…Although clinical diagnosis by imaging methods such as MRI and ultrasound is usually successful in locating and assessing the malignant potential of singular/bilateral lesions of the parotid glands, the difficulty of correct preoperative radiological assessment of multiple ipsilateral parotid tumors is well known [ 7 , 19 ]. A definitive diagnosis is usually made only during histological tissue examination, as in the present case [ 7 , 11 ].…”

Section: Discussionmentioning

confidence: 99%

Uncommon Coexistence of Pleomorphic Adenoma and Warthin’s Tumor in a Painfully Swollen Left Parotid Gland: A Surgical Case Report

Klamminger,

Issing,

Burck

et al. 2023

Am J Case Rep

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Patient: Female, 54-year-old Final Diagnosis: Synchronous benign pleomorphic adenoma and Warthin’s tumor Symptoms: Progressive and painful swelling of the left parotid gland for the last six months with a marked increase in size in recent weeks Clinical Procedure: Surgery Specialty: Pathology Objective: Rare coexistence of disease or pathology Background: Benign pleomorphic adenoma is the most common primary tumor of the salivary glands and mainly arises in the parotid gland. Warthin’s tumor, or papillary cystadenoma lymphomatosum, represents <30% of benign parotid tumors. The simultaneous occurrence of multiple parotid tumors is rarely described – depending on the corresponding histology (different/identical), the time of their occurrence (synchronous/metachronous), as well as their location (unilateral/bilateral), multiple parotid tumors can be further sub-classified. Case Report: We describe the case of a 54-year-old female patient with progressive and painful swelling of the left parotid gland for the last 6 months. During extra-oral examination, a bulging, displaceable mass of approximately 3 cm was determined. A subsequent MRI (magnetic resonance imaging) examination revealed a multifocal lesion but failed to provide a decisive clue as to the tumor entity of the lesion, and a lateral (superficial) parotidectomy was performed. Postoperative histomorphological interpretation allowed the final pathological diagnosis of synchronous, unilateral occurrence of a pleomorphic adenoma as well as a Warthin’s tumor. Conclusions: This report presents a rare case of synchronous unilateral parotid tumors and supports that benign pleomorphic adenoma and Warthin’s tumor are the most common associations. Since clinical examination, MRI imaging, and even cytological assessment could be misleading in the detection of synchronous ipsilateral multiple parotid gland tumors, our report also highlights the importance of timely and accurate diagnosis with histo-pathology to plan surgery and to exclude malignant transformation, which is a rare but important association with both types of primary salivary gland tumor.

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Section: Discussionmentioning

confidence: 99%

Uncommon Coexistence of Pleomorphic Adenoma and Warthin’s Tumor in a Painfully Swollen Left Parotid Gland: A Surgical Case Report

Klamminger,

Issing,

Burck

et al. 2023

Am J Case Rep

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“…Preoperative imaging tests, clinical examination, and careful intraoperative palpation are important for accurate diagnosis and treatment of multiple synchronous neoplasms in the ipsilateral parotid gland (1)(2)(3)8,9). In this study, CT was mainly used for economic reasons, but MRI is preferred for diagnosing multiple parotid tumors (3).…”

Section: Discussionmentioning

confidence: 99%

“…Surgery is indicated for multiple synchronous neoplasms involving the ipsilateral parotid gland (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11). Complete resection with sufficient safe margins is important (3).…”

Section: Discussionmentioning

confidence: 99%

“…The majority of parotid neoplasms are benign, unilateral, and single lesion (1)(2)(3)(4). Synchronous neoplasms refer to the development of one or more neoplasms that occur simultaneously but distinct from each other in the parotid gland (2).…”

Section: Introductionmentioning

confidence: 99%

“…Synchronous neoplasms refer to the development of one or more neoplasms that occur simultaneously but distinct from each other in the parotid gland (2). Therefore, multiple synchronous parotid neoplasms are very rare with a frequency of about 0.7% (1)(2)(3)(4)(5)(6)(7)(8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

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Multiple synchronous neoplasms in the ipsilateral parotid gland: case series

Park¹,

Jang²,

Lee³

et al. 2022

Ann Palliat Med

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Background: Multiple synchronous neoplasms in the ipsilateral parotid gland are very rare. We intend to analyze the clinical characteristics and treatment results of multiple synchronous neoplasms in the ipsilateral parotid gland managed at our hospital. Methods:The study included 21 patients of multiple synchronous neoplasms in the ipsilateral parotid gland from January 2010 to December 2020.Results: Twenty-one cases of multiple synchronous neoplasms in the ipsilateral parotid gland were identified among 994 cases of parotid surgery, with a frequency of 2.1%. Multiple synchronous neoplasms in the ipsilateral parotid gland occurred in all males and one female. Except for one case, all of them involved histopathologic neoplasms. Warthin tumor (n=19, 90.5%) was the most common. Among 21 lesions, there were 9 patients of right parotid gland, 4 patients of left parotid gland, and 4 patients of bilateral parotid gland. The main symptoms were slowly enlarging mass within the parotid gland (n=20), followed by incidental detection (n=1).Conclusions: Clinicians should be aware of the possibility of multiple synchronous neoplasms in the ipsilateral parotid gland. Preoperative imaging tests, clinical examinations, and careful palpation during surgery are important for accurate diagnosis and treatment.

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Radiological features of head and neck mammary analogue secretory carcinoma: 11 new cases with a systematic review of 29 cases reported in 28 publications

Kurokawa

Baba

et al. 2021

Neuroradiology

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Concurrent presence of secretory carcinoma and Warthin’s tumor in ipsilateral parotid gland

Cited by 5 publications

References 17 publications

Uncommon Coexistence of Pleomorphic Adenoma and Warthin’s Tumor in a Painfully Swollen Left Parotid Gland: A Surgical Case Report

Uncommon Coexistence of Pleomorphic Adenoma and Warthin’s Tumor in a Painfully Swollen Left Parotid Gland: A Surgical Case Report

Multiple synchronous neoplasms in the ipsilateral parotid gland: case series

Radiological features of head and neck mammary analogue secretory carcinoma: 11 new cases with a systematic review of 29 cases reported in 28 publications

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