Concurrent reactivation of latent EBV with hepatitis A can affect clinical feature of childhood hepatitis

Kim, S. Y.; Ryu, Ik-Han; Baek, Song-Ee; Chung, Ki Sup; Koh, Hong

doi:10.1111/j.1651-2227.2010.01752.x

Cited by 5 publications

(2 citation statements)

References 21 publications

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“…Another possible limitation is that subjects in the current asthma cohort study were derived from five different studies and one of them was carried out among relatively young adults (15 years old in the year 2000) [14, 15]. The total response rate was approximately 61 % but in the young adult population study it was as low as 44 %, which may cause some under-representation of young asthmatics in the present study.…”

Section: Discussionmentioning

confidence: 92%

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Impact of occupational exposures on exacerbation of asthma: a population-based asthma cohort study

et al. 2016

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BackgroundAsthma is a prevalent chronic disease and occupation contributes to approximately 15 % of cases among adults. However, there are still few studies on risk factors for work-exacerbated asthma. The current study investigated the association between asthma exacerbations and occupational exposures.MethodsThe study comprised all currently working adults (n = 1356) who reported ever asthma in prior population-based cohorts. All subjects completed a questionnaire about exposures, occupations and exacerbations of asthma. Exposure to high and low molecular weight agents, irritating agents and asthmagens were classified using the asthma-specific job exposure matrix for northern Europe (N-JEM). Severe exacerbation of asthma was defined as sought emergency care at a hospital, admitted to a hospital overnight, or made an urgent visit to a primary care physician or district medical office due to breathing problems during the last 12 months. Moderate exacerbation was defined as both being not severe exacerbation and an additional visit to a primary care physician or district medical office, or had extra treatments with corticosteroid tablets. Mild exacerbation was defined as being neither severe nor moderate exacerbation, and increasing usage of inhaled corticosteroids.Multiple logistic regression was applied to investigate the association between exacerbation of asthma and occupational exposures while adjusting for potential confounders.ResultsApproximately 26 % of the working asthmatics reported exacerbation, and more than two-thirds of them had moderate or severe exacerbation. From 23 to 49 % of the asthmatics reported occupational exposure to a variety of different types of agents. Exposure to any gas, smoke or dust (OR 1.7[95 % CI 1.2–2.6]) was associated with severe exacerbation of asthma, as were organic dust (OR 1.7[1.2–2.5]), dampness and mold (OR 1.8[1.2–2.7]), cold conditions (OR 1.7[1.1–2.7]), and a physically strenuous job (OR 1.6[1.03–2.3]). Asthmagens and low molecular weight agents classified by the N-JEM were associated with mild exacerbation, with OR 1.6[1.1–2.5] and OR 2.2[1.1–4.4], respectively.ConclusionsSelf-reported exposure to any gas, smoke or dust, organic dust, dampness and mold, cold conditions and physically strenuous work, and jobs handling low molecular weight agents were associated with exacerbation of asthma. Reduction of these occupational exposures may help to reduce exacerbation of asthma.

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Section: Discussionmentioning

confidence: 92%

“…The present study is based on an asthma cohort called Asthma-X that was derived from four different Swedish population-based studies: ADONIX [13], ALL000 [14, 15], MAP [16] and the Gothenburg part from the RHINE study [17], and one case-control study called M10 [18]. …”

Section: Methodsmentioning

confidence: 99%

Impact of occupational exposures on exacerbation of asthma: a population-based asthma cohort study

et al. 2016

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The mediating role of sleep in the fish consumption – cognitive functioning relationship: a cohort study

Liu

Cui

et al. 2017

Sci Rep

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Greater fish consumption is associated with improved cognition among children, but the mediating pathways have not been well delineated. Improved sleep could be a candidate mediator of the fish-cognition relationship. This study assesses whether 1) more frequent fish consumption is associated with less sleep disturbances and higher IQ scores in schoolchildren, 2) such relationships are not accounted for by social and economic confounds, and 3) sleep quality mediates the fish-IQ relationship. In this cohort study of 541 Chinese schoolchildren, fish consumption and sleep quality were assessed at age 9–11 years, while IQ was assessed at age 12. Frequent fish consumption was related to both fewer sleep problems and higher IQ scores. A dose-response relationship indicated higher IQ scores in children who always (4.80 points) or sometimes (3.31 points) consumed fish, compared to those who rarely ate fish (all p < 0.05). Sleep quality partially mediated the relationship between fish consumption and verbal, but not performance, IQ. Findings were robust after controlling for multiple sociodemographic covariates. To our knowledge, this is the first study to indicate that frequent fish consumption may help reduce sleep problems (better sleep quality), which may in turn benefit long-term cognitive functioning in children.

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The role of omega-3 fatty acids in child development

Osendarp

2011

OCL

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Concurrent reactivation of latent EBV with hepatitis A can affect clinical feature of childhood hepatitis

Abstract: Concurrent reactivation of latent EBV and HAV infections is common. EBV reactivation with HAV infection adversely affects the clinical feature of hepatitis. Therefore, we should keep in mind that the concurrence especially in older children may cause worse injury to the liver.

Cited by 5 publications

References 21 publications

Impact of occupational exposures on exacerbation of asthma: a population-based asthma cohort study

Impact of occupational exposures on exacerbation of asthma: a population-based asthma cohort study

The mediating role of sleep in the fish consumption – cognitive functioning relationship: a cohort study

The role of omega-3 fatty acids in child development

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