Conditions of Skin and Intestine Microbiotes in Patients With Psoriasis

Ємченко, Я.О.; Іщейкін, К.Є.; Кайдашев, І.П.; Мороховець, Г.Ю.

doi:10.31718/mep.2022.26.1-2.07

Cited by 2 publications

(1 citation statement)

References 46 publications

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“…Медичному працівнику дуже важливо пояснити, що захворювання шкіри можна вилікувати під час проведення певних заходів [13,14,15,16]. А саме моніторинг та проведення діагностики на ранніх стадіях захворювання; злагодженою співпрацю лікарів на підприємстві та домашніх лікарів при лікуванні професійних захворювань шкіри; заміною матеріалів, що шкідливо впливають на шкіру, хімічно спорідненими, але менш аллергізуючими (речовини -збудники замінюють речовинами, що менше подразнюють шкіру); проведенням інактивації алергенів; алергени замінюють м'якими алкалоїдами/нейтральними оксидантами або впроваджують використання синтетичних рукавичок; впровадженням у виробництво технічних заходів (герметичне обладнання, застосування миючих автоматів, механізація та автоматизація виробництва); постійним поліпшенням устаткування; проведення організаційних заходів з періодичною зміною робочих місць з вологими умовами праці на місця з сухими умовами праці, що забезпечують більш тривалий термін висихання виробів; застосування засобів індивідуального захисту; застосування рукавичок із спеціальним захисним шаром для шкіри (вживання захисних кремів перед початком роботи, адекватне очищення шкіри, догляд за шкірою для регенерації шкіри після закінчення роботи, своєчасне оброблення дрібних травм); створення цільових груп: дослідження з охорони праці молоді, положення професійних спілок з професійних захворювань; проведення періодичних медичних оглядів та диспансеризації.…”

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Main Social Directions of Professional Dermatology

Yemchenko¹,

Ishcheykin²,

Morokhovets³

et al. 2022

Act. Probl. of the Modern Med.

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Despite the rapid progress of modern medical science and the introduction of scientific results into the practice of health care in Ukraine, life expectancy is steadily decreasing and life quality is deteriorating. The causes of this discrepancy lie first and foremost in the social plane. Currently, the Ukrainian health care system is taking the first steps out of its crisis at the national level; in particular, the increase in morbidity and mortality of the population in Ukraine is recognized as a priority for the state policy in the field of healthcare, as well as the improvement of the environmental conditions, housing and occupational condition of the population. EU investments are being attracted, new forms and methods of providing medical assistance to the population in many fields of medicine are being introduced. Nevertheless, social aspects of occupational medicine have not received adequate coverage. Among them there are such sections of occupational hygiene and disease prevention as occupational physiology, occupational hygiene, occupational pathology and some others. Today, despite the wide coverage of the clinical picture, pathomorphology and methods of treatment of occupational skin diseases and the social aspects of occupational medicine have not been thoroughly investigated. Problem of social analysis of the problem of occupational skin diseases occupies a prominent place. Therefore, the health care system of Ukraine requires urgent and radical reformation in general and in the field of dermatology in particular.

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Main Social Directions of Professional Dermatology

Yemchenko¹,

Ishcheykin²,

Morokhovets³

et al. 2022

Act. Probl. of the Modern Med.

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Role of Local Probiotics as New Therapeutic Approach in Treatment of Skin Diseases

Bezeha¹,

Yemchenko²,

Vasylyeva³

et al. 2022

Act. Probl. of the Modern Med.

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Probiotics are live microorganisms that, when taken in the right amount, help maintain a healthy state of the body. Natural microorganisms usually make up first-generation probiotics, while genetically engineered strains are secondary probiotics. The importance of microorganisms to human health dates back to the era when Louis Pasteur first discovered the importance of fermentation and drew attention to the fact that consuming fermented foods could be beneficial for health and longevity. Oral and topical probiotics are used to treat skin conditions. Microorganisms live inside our body, both in the intestines and on the skin. Commensal bacteria play a vital role in human health; they also help maintain a healthy immune system. The skin microbiome consists of several types of microorganisms. Any imbalance of these microorganisms leads to skin diseases. Probiotics are well known for their clinical use in certain skin diseases, and probiotic bacterial therapy may have great potential in the prevention and treatment of several skin diseases [3]. Studies have established a link between a disrupted gut microbiome and inflammatory skin diseases, thereby increasing the potential of oral probiotics as a treatment option for skin disorders [4]. However, there is very little information and clinical studies that have examined the effectiveness of topical probiotic products. The use of probiotic bacteria can help strengthen the skin natural barrier by having a direct effect at the site of application. This may be due to resident bacteria and probiotic bacteria that produce certain antimicrobial aminopeptides that promote the skin's immune response and help eliminate pathogens. Some cosmetic preparations can contribute to the maintenance of a normal skin microbiome, being selective in their activity [5]. Topical probiotics have been known to be used to support a healthy skin microbiome since the early 20th century, and the last decade has seen a dramatic increase in commercially available topical probiotics [6]. However, despite the growing popularity of these topical agents, there are currently insufficient clinical efficacy trials to establish their clinical efficacy, so we aimed to write a detailed review on the use of probiotics in the treatment of skin diseases. In our article, we have detailed information about the normal skin microbiome, various skin disorders, and the topical probiotics commonly used to treat these skin conditions.

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Conditions of Skin and Intestine Microbiotes in Patients With Psoriasis

Cited by 2 publications

References 46 publications

Main Social Directions of Professional Dermatology

Main Social Directions of Professional Dermatology

Role of Local Probiotics as New Therapeutic Approach in Treatment of Skin Diseases

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