Conducting polymers of decanedioic acid bis-(4-pyrrol-1-yl-phenyl) ester

Çırpan, Ali; Guner, Y.; Toppare, Levent

doi:10.1016/j.matchemphys.2004.01.014

Cited by 8 publications

(3 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the recent years, the field of electrically conducting polymers, such as polypyrrole (PPy), polythiophene (PTh), and polyaniline (PANI), has been studied extensively 1. These polymers are used in many applications, such as batteries,2 electrochromics,3, 4 gas separation membranes,5 electromagnetic interference shielding,6, 7 sensors,8, 9 and metal protection against corrosion 10, 11…”

Section: Introductionmentioning

confidence: 99%

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells

Thakur

Dittrich

Prakash

et al. 2012

Intl Journal of Cancer

View full text Add to dashboard Cite

FK866 is a specific inhibitor of NAMPT and induces apoptosis of leukemic cells by depletion of intracellular NAD+. Since up-regulation of NAMPT is associated with several cases of cancers, including leukemias, we asked whether in leukemic cells inhibition of NAMPT involves p53 pathway. We observed that FK866 induced apoptosis and reduced cell proliferation in NB-4, OCI-AML3 and MOLM-13 cell lines. In contrast, the leukemia cell lines, K-562 and Kasumi, containing nonfunctional p53 were relatively unaffected by FK866 treatment. Importantly, direct inhibition of sirtuins significantly reduced the viability of NB-4, OCI-AML3 and MOLM-13 cell lines. Activation of p53 by FK866 involved increased acetylation of p53 at lysine 382 with subsequent increase in the expression of p21 and BAX. Further, knockdown of p53 attenuated the effects of FK866 on apoptosis and cell cycle arrest, which was partly associated with decreased expression of p21 and BAX. Our results suggest the role of p53 acetylation pathway in the anti-leukemic effect of FK866.

show abstract

Section: Introductionmentioning

confidence: 99%

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells

Thakur

Dittrich

Prakash

et al. 2012

Intl Journal of Cancer

View full text Add to dashboard Cite

show abstract

“…In the present study, decanedioic acid bis(4‐pyrrole‐1‐yl‐phenyl) ester (DAPE) was used to synthesize copolymers with pyrrole to form a matrix (Ppy/DAPE) for immobilization of PPO. Synthesis and characterization of the copolymer of DAPE with pyrrole were described (Scheme ) in an earlier study 14. Immobilization of PPO was achieved by electropolymerization of pyrrole with a previously DAPE‐coated platinum (Pt) electrode.…”

Section: Methodsmentioning

confidence: 99%

Enzyme electrodes for determination of total phenolic capacity of red wines

Kiralp

Çırpan

Toppare

2005

J of Applied Polymer Sci

View full text Add to dashboard Cite

A tyrosinase-modified electrode, based on physical entrapment of enzyme in copolymer matrix of decanedioic acid bis(4-pyrrol-1-yl-phenyl) ester (DAPE) with pyrrole was constructed and used to investigate the total amount of phenolics in red wines. Kinetic parameters, V max , and K m , were determined. Also, temperature, pH optimizations, operational stability and shelf life of the enzyme electrode were examined. Surface morphologies of the films were studied by scanning electron microscope.

show abstract

“…Application of these polymers include light-emitting diodes [2], electrochromic [3] and electronic devices, battery *Corresponding author. E-mail: nasserarsalani@yahoo.com electrodes [4][5][6], field-effect transistors [7], sensors [8,9], plastic photovoltaic devices [10] and metal protection against corrosion [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of poly(3-methylthiophene) in the presence of 1-(2-Pyrrolyl)-2-(2-thienyl) ethylene by electropolymerization

Kiani

Arsalani

Hosseini

et al. 2008

JICS

View full text Add to dashboard Cite

In this study, the electropolymerization of 3-methylthiophene (3-MT) was preformed in the presence of a catalytic amount 1-(2-pyrrolyl)-2-(2-thienyl) ethylene (PTE) by cyclic voltammetry in acetonitrile as a solvent and lithium perchlorate as the electrolyte on a glassy carbon (GC) electrode. First, PTE was synthesized via the Wittig reaction. The addition of a catalytic amount of PTE during the electropolymerization of 3-MT changes the cyclic voltammograms such that the analysis of cyclic voltammograms of poly(3-MT) shows a considerable increase in the electroactivity and redoxability. Furthermore, the presence of PTE during the electropolymerization of 3-MT increases the polymerization rate. The CV measurement of the electron transfer ferro/ferricyanide redox system using different modified GC electrodes shows that the rate of charge transfer for poly(3-MT) in the presence of PTE is greater than that of poly(3-MT) alone. The conductivity of the obtained polymers was determined by electrochemical impedance spectroscopy (EIS) in 3.5% NaCl (w/v) solutions. With the application of Zview(II) software to the EIS, we estimate the parameters of the proposed equivalent circuit, based on a physical model for the electrochemical behavior of coatings on the GC electrode, to be 15739 ohm cm 2 for the charge transfer resistance (R ct ) for poly(3-MT) alone and 9700 ohm cm 2 for poly(3-MT) in the presence of PTE. Thus, the film of poly(3-MT) formed in the presence of PTE is more conductive.

show abstract

Conducting polymers of decanedioic acid bis-(4-pyrrol-1-yl-phenyl) ester

Cited by 8 publications

References 16 publications

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells

Enzyme electrodes for determination of total phenolic capacity of red wines

Synthesis of poly(3-methylthiophene) in the presence of 1-(2-Pyrrolyl)-2-(2-thienyl) ethylene by electropolymerization

Contact Info

Product

Resources

About