Condylomata Acuminata in Children

Stefanaki, Christina; Barkas, George; Valari, Manthoula; Bethimoutis, George; Nicolaidou, Electra; Vosynioti, Vasiliki; Kontochristopoulos, George; Papadogeorgaki, Helen; Verra, Prokopia; Κατσαρού, Αλεξάνδρα

doi:10.1097/inf.0b013e318245a589

Cited by 23 publications

(27 citation statements)

References 7 publications

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“…Although most HPV infections are subclinical, condyloma acuminata may be a visible manifestation of HPV infection among children less than 4 years old. 7 , 12 The mean age at presentation for anogenital warts in children ranges from 2.8 to 5.6 years in a reported case series. 7 The symptoms of our case had been observed by her mother at 12 months of age.…”

Section: Discussionmentioning

confidence: 97%

“… 7 , 12 The mean age at presentation for anogenital warts in children ranges from 2.8 to 5.6 years in a reported case series. 7 The symptoms of our case had been observed by her mother at 12 months of age. The transmission routes of HPV infection in children are not as clear as in adults.…”

Section: Discussionmentioning

confidence: 97%

“…Imiquimod, although not approved for the pediatric population, may be a choice for cases unresponsive to conventional treatment. 2 , 7-11 Herein, we present the case of a 27-month old girl with condyloma acuminata due to HPV type 16, which was successfully treated with topical imiquimod therapy.…”

Section: Introductionmentioning

confidence: 99%

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Giant condyloma acuminate due human papilloma virus type 16 in an infant successfully treated with topical imiquimod therapy

et al. 2015

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Anogenital warts related to human papillomavirus (HPV) have been observed in children. Definition of the transmission mode, therapy, and follow-up for long term potential complications is important. A 27-month old girl was admitted with multiple pedunculated red-purple colored cauliflower-like lesions of 1.5 years duration. Clinical/histopathological and microbiological diagnosis was condyloma acuminate due to HPV type 16. After 12 weeks of imiquimod 5% cream application (pea-sized) overnight three times per week, the perianal warts had completely disappeared. The mode of transmission of HPV 16 in our case was probably horizontal, related to the sharing of common personal hygiene items in the women’s shelter. We report herein the case of an infant living in a women’s shelter with giant condyloma acuminata due to HPV 16, which was successfully treated with topical imiquimod therapy. This patient should be followed up for recurrence and potential malignant lesions related to HPV type 16.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 97%

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Giant condyloma acuminate due human papilloma virus type 16 in an infant successfully treated with topical imiquimod therapy

et al. 2015

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“…Although abuse must be considered, it is also possible that pediatric anogenital condyloma can occur from vertical transmission, autoinoculation, heteroinoculation, or fomites. 19 A female infant may be found to have a flesh-colored papule anterior to the anus that represents a lesion termed infantile perianal pyramidal protrusion (IPPP). The lesion may raise concern of condyloma accuminatum, 20 and hence it is important to be aware of this entity.…”

Section: Pediatric Benign Tumors and Tumor-like Lesions Involving Thementioning

confidence: 99%

Benign Tumors and Tumor-like Lesions of the Vulva

Heller

2015

Clinical Obstetrics &Amp; Gynecology

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“…Once a child has had AGWs, the appearance of new lesions after spontaneous resolution or treatment does not necessarily indicate a new exposure [24]. One can choose between cryotherapy, electrodessication, podophyllotoxin, or imiquimod [25].…”

Section: Introductionmentioning

confidence: 99%

Genital Warts in Infants and Children <br>—Re-Evaluation of Podophylline 15% as an Effective Topical Therapy

Sharquie¹,

Noaimi²,

Almallah³

2014

JCDSA

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Background: Condylomataacuminata is an infection caused by Human Papilloma Virus, rarely reported in infants and children. Podophylline as a treatment for this condition has been used cautiously in this age group. Objective: To report the cases of anogenital warts including condy lomataacuminata in infants and children and to evaluate the effectiveness and side effects of 15% podophyllin in treatment of genital warts. Patient and Methods: Thirty infants and young children were seen in Department of Dermatology and Venereology-Baghdad Teaching Hospital in this case descriptive and therapeutic trial, in the period from January 2011 to August 2012. Their ages ranged from 8-72 (30.43 ± 15.85) months, 20 females and 10 males with a female:male ratio of 2:1. The duration of the disease ranged from 1-12 (5.26 ± 4.00) months. All demographics data were recorded in this study. History and examination were carried out to all patients. Family members including mothers were assessed about the presence of any type of viral warts in other location of body. Podophyllin (15%) in tincture benzoin was applied once weekly to all viral warts and the parents advised to wash out after 2 hours of application. The number of applications was repeated until full recovery. Follow-up after recovery was carried out for 6 months to watch for any relapse and to record local or systemic side effects. Results: The clinical pictures were mostly acondylomata acuminata in a form of cauliflower like warts in 20 (73.33%) patients, while in 10 (26.77%) patients there were ordinary verruca vulgaris like warts. The location of warts was perianal in 23 (76.66%) patients, genital only in 2 (6.66%) patients, and mixed in 5 (16.66%) patients. Topical applications of podophyllin 15% gave a full recovery in 27 (90%) patients, while in 3 (10%) patients there was partial response. The number of applications ranged from 1-4 (2.7 ± 1.42) applications. Follow up for 6 months after recovery showed relapse in only one patient, and no side effects were reported in any patients. Conclusion: There is upsurge of cases of anogenital warts among infants and children. Podophyllin (15%) in tincture benzoin is an effective therapy and no local or systemic side effects were recorded in any case.

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Condylomata Acuminata in Children

Cited by 23 publications

References 7 publications

Giant condyloma acuminate due human papilloma virus type 16 in an infant successfully treated with topical imiquimod therapy

Giant condyloma acuminate due human papilloma virus type 16 in an infant successfully treated with topical imiquimod therapy

Benign Tumors and Tumor-like Lesions of the Vulva

Genital Warts in Infants and Children <br>—Re-Evaluation of Podophylline 15% as an Effective Topical Therapy

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Condylomata Acuminata in Children

Cited by 23 publications

References 7 publications

Giant condyloma acuminate due human papilloma virus type 16 in an infant successfully treated with topical imiquimod therapy

Giant condyloma acuminate due human papilloma virus type 16 in an infant successfully treated with topical imiquimod therapy

Benign Tumors and Tumor-like Lesions of the Vulva

Genital Warts in Infants and Children &lt;br&gt;—Re-Evaluation of Podophylline 15% as an Effective Topical Therapy

Contact Info

Product

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Genital Warts in Infants and Children <br>—Re-Evaluation of Podophylline 15% as an Effective Topical Therapy