This file was dowloaded from the institutional repository Brage NIH -brage.bibsys.no/nih Huang, T., Larsen, K. T., Møller, N. C., Ried-Larsen, M., Frandsen, U., Andersen, L. B. (2015
Methods:One hundred and fifteen children were recruited in Odense, Denmark (2011Denmark ( -2014. The participants were randomly allocated to either the day camp intervention arm (DCIA) or the standard intervention arm (SIA). The intervention for the DCIA comprised a 6-week camp intervention and a 46-week family-based intervention. The SIA was offered one weekly physical activity session for 6 weeks and one educational meeting. C-reactive protein (CRP), monocyte chemoattractant protein-1 (MCP1), leptin, and adiponectin were measured in serum at baseline, 6 weeks and 52 weeks.Results: Compared with the SIA, the reductions in CRP (P=0.003) and leptin (p<0.001) were larger in the DCIA at 6 weeks. The intervention effects on leptin were significantly mediated by the changes in body fat mass. No intervention effects on CRP and leptin were seen at 52 weeks. No between-group differences in changes in MCP1 and adiponectin were observed at 6 weeks or 52 weeks.
Conclusions:The 6-week camp intervention resulted in reductions in CRP and leptin. The intervention effects did not persist to 52 weeks. The intervention effect on leptin was explained by the changes in body fat mass.