Confluent and Reticulated Papillomatosis

Scheinfeld, Noah

doi:10.2165/00128071-200607050-00004

Cited by 79 publications

(105 citation statements)

References 56 publications

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“…insulin resistance), and genetic predisposing factors, have been speculated to be responsible for the pathogenesis of CRP, but none has been clearly shown to be causative, limiting evidence-based selection of therapeutic options. [2][3][4][5] In our case, the putative triggers have not been detected. Among the CRP cases reported in the last decade, just one case involved spontaneous regression, 3 but no detailed description of the clinical course was provided.…”

contrasting

confidence: 54%

Chronology of confluent and reticulated papillomatosis: Spontaneous regression in a case after long‐term follow‐up may imply transient nature of the condition

Tomo

Amagai

Ohyama

2015

The Journal of Dermatology

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Chronology of confluent and reticulated papillomatosis: Spontaneous regression in a case after long-term follow-up may imply transient nature of the condition Dear Editor, Confluent and reticulated papillomatosis (CRP) is a rare skin disorder that was first described by Gougerot and Carteaud in 1927. 1 Typically, CRP develops in young adults and presents as persistent brown papules and plaques that are confluent centrally and reticulated peripherally. Herein, we report an extremely rare case of CRP in which spontaneous regression was achieved after more than 3 years' follow-up. To the best of our knowledge, detailed sequential clinical images of self-healing CRP has not been previously reported in the literature. In histology, hyperkeratosis with focal accentuation, papillomatosis, moderate acanthosis, and mild dermal perivascular mononuclear cell infiltration were noted (hematoxylin-eosin, original magnifications: 9100). (c) Neither fungus nor bacterium was detected in the stratum corneum (hematoxylin-eosin, original magnifications: 9200).

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contrasting

confidence: 54%

Chronology of confluent and reticulated papillomatosis: Spontaneous regression in a case after long‐term follow‐up may imply transient nature of the condition

Tomo

Amagai

Ohyama

2015

The Journal of Dermatology

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“…Melanogenesis and transient epidermal hyperplasia can be induced by ultraviolet radiation. It may be also a variant of cutaneous amyloidosis [1][2][3] . Malassezia colonization can be detected, and improved with antifungal treatment.…”

Section: Discussionmentioning

confidence: 99%

“…Side effects of azithromycin are fewer than minocycline. In addition, macrolide and tetracycline groups have both antimicrobial and anti-inflammatory effects via inhibition of metalloproteinase, hydrolase, phospholipase A2, tumor necrosis factor alpha, interleukin (IL)-1β, and IL-6 as well as suppression of IL-8 and neutrophil oxidative burst 1,3 . Selenium sulphide can be effective due to keratolytic effect.…”

Section: Discussionmentioning

confidence: 99%

Successful treatment of confluent and reticulated papillomatosis with tetracycline and mupirocin

Ataş¹,

Keseroglu²,

Gönül³

et al. 2018

TURKDERM

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“…Ayrıca tedavide isotretinoin ve asitretin kullanılabileceği de bildirilmiştir. Diğer taraftan bakteriyel ajanlara duyarlılıktan bahsedildiği için azitromisinin, fusidik asit, klaritromisin ve eritromisin de tedavi ajanları arasındadır 7 . Biz minosiklin tedavisine klinik yanıt vermeyen ve asitretin tedavisi ile iyileşen bir GCS olgusu sunuyoruz.…”

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Gougerot-Carteaud syndrome treated with acitretin: A case report

Demir¹,

Ağar²,

Karstarlı³

et al. 2017

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Gougerot-Carteaud syndrome (GCS) is a rarely seen dermatosis characterized by reticular and pigmented plaques with a tendency to merge with each other in areas such as the neck, upper body, and axilla in young adults. A 20-year-old male patient presented to the dermatology outpatient clinic with the complaints of itching and brown patches affecting the trunk, back and the neck. He had no endocrine diseases and used no drugs. Dermatological examination revealed reticulated, hyperpigmented, verrucous papules and plaques on the anterior surface of his trunk, upper back, and neck region. No fungal elements were encountered in the potassium hydroxide examination. Histopathologically, basket-like hyperkeratosis, papillomatosis, mild acanthosis, and hyperpigmentation in the basal layer were detected. Minocycline treatment was initiated at a dose of 100 mg/daily. At the three-month follow-up visit, minocycline treatment was terminated due to lack of clinical response, and 30 mg/day acitretin treatment was initiated. The lesions showed marked improvement except for a slight hyperpigmentation in the first month of the treatment. We report here a case of GCS in which acitretin was started due to clinical unresponsiveness to minocycline treatment and, substantially, a favorable result was obtained in a short time. Keywords: Gougerot-Carteaud syndrome, confluent and reticulated papillomatosis, acitretin Abstract GirişGougerot-Carteaud sendromu (GCS); konfluent retiküler papillomatozis olarak da bilinir. Genç erişkinlerde boyun, üst gövde, aksilla gibi bölgelerde birbiri ile birleşmeye meyilli, retiküler ve hiperpigmente plaklarla karakterize nadir görülen bir dermatozdur 1 . Hastalığın malassezia furfur, staphylococcus veya propionibacterium acnes'e karşı gelişen anormal bir konakçı yanıtı olduğu düşünülmüştür. Diğer taraftan obezite, tip 2 diyabet, hirşutismus, Cushing sendromu, menstruel disfonksiyon, vitamin A eksikliği, genetik yatkınlık, fotosensitivite, kutanöz amiloidoz ve Gougerot-Carteaud sendromu (GCS) genç erişkinlerde boyun, üst gövde, aksilla gibi bölgelerde birbiri ile birleşmeye meyilli, retiküler, pigmente plaklarla karakterize nadir bir dermatozdur. Yirmi yaşında erkek hasta gövdesinde ve sırtında kahverengi renk değişikliği ve kaşıntı şikayeti ile başvurdu. Özgeçmişinde endokrinolojik bir hastalığı olmadığı ve herhangi bir ilaç kullanmadığı öğrenildi. Dermatolojik muayenesinde gövde ön ve arka yüzde, boyun bölgesinde hiperpigmente retiküler, verüköz papül ve plaklar mevcuttu. Potasyum hidroksit incelemede mantar elemanlarına rastlanmadı. Histopatolojide sepetsi hiperkeratoz, papillomatoz, hafif akantoz, bazal tabakada hiperpigmentasyon tespit edildi. 100 mg/gün minosiklin tedavisi başlandı. Tedavinin 3. ayında klinik yanıt alınamaması nedeni ile minosiklin tedavisi sonlandırıldı ve 30 mg/ gün asitretin tedavisi başlandı. Tedaviye başladıktan 1 ay sonra lezyonların hafif hiperpigmentasyon bırakarak iyileştiği tespit edildi. Biz burada minosikline klinik yanıtsızlık nedeniyle asitretin tedavisi başlanan ve kı...

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Confluent and Reticulated Papillomatosis

Cited by 79 publications

References 56 publications

Chronology of confluent and reticulated papillomatosis: Spontaneous regression in a case after long‐term follow‐up may imply transient nature of the condition

Chronology of confluent and reticulated papillomatosis: Spontaneous regression in a case after long‐term follow‐up may imply transient nature of the condition

Successful treatment of confluent and reticulated papillomatosis with tetracycline and mupirocin

Gougerot-Carteaud syndrome treated with acitretin: A case report

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