Conformal hypofractionated radiotherapy for dogs with large adrenal tumours

Maruo, Takuya; Ito, Tetsuro; Kanai, Eiichi; Nemoto, Yasuhiro; Nishiyama, Yuta

doi:10.1136/vetreccr-2019-000942

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…Hypofractionated stereotactic radiotherapy for adrenal tumors with vascular invasion has been recently described in several veterinary case series, with tumors decreasing in size and dogs having survival times over a year. 13,14 This treatment, if available, is a potential alternative to surgery for dogs with adrenal tumors that are either at high risk (such as the case described in this report) or deemed inoperable.…”

Section: Discussionmentioning

confidence: 96%

Balloon catheter as an extraction device for caudal vena cava adrenal tumor thrombectomy in a dog: A case report

2022

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Objective To report the use of a balloon catheter as an extraction device for a posthepatic caval thrombus in a dog with a right adrenal tumor. Animals Twelve‐year‐old male neutered Chihuahua mix dog. Study design Case report Methods The dog presented for the evaluation of a hepatic mass. Computed tomography of thorax and abdomen was performed, and a right lateral liver lobe mass and a right adrenal mass were noted. The adrenal mass had a caval thrombus extending almost to the level of the right atrium. Traditional methods of tumor thrombectomy were unsuccessful. Extraction of the thrombus was facilitated by passing a balloon catheter through the caudal vena cavotomy until it was cranial to the thrombus, inflating the balloon and slowly withdrawing the catheter. Results A malignant pheochromocytoma was diagnosed on histology. The dog had a subjectively assessed good quality of life until it was euthanized 118 days postoperatively for acute dyspnea. Conclusion Balloon catheter‐assisted thrombectomy was successful in removing an extensive caval thrombus that was otherwise difficult to extract via conventional methods. This technique can be considered in cases with extensive tumor thrombus either as a method of choice or when other methods of thrombus extraction have failed.

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Section: Discussionmentioning

confidence: 96%

Balloon catheter as an extraction device for caudal vena cava adrenal tumor thrombectomy in a dog: A case report

2022

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“…In the present study, it was investigated whether the mobility of abdominal organs by respiration showed a significant difference between the ventral recumbency and dorsal, Rt., and Lt. lateral recumbency. In veterinary medicine, radiation therapy has often been performed in a ventral position in patients with various tumors such as heart base tumor, prostatic carcinoma, hepatocellular carcinoma, and adrenal gland tumor (13,17,19,23). In addition, as the ventral recumbency has good posture reproducibility, a control group has been set to the ventral recumbency (16).…”

Section: Discussionmentioning

confidence: 99%

Assessment of Abdominal Organs Movement by Respiration Using Computed Tomography in Dogs: A Pitfall for Radiation Therapy

Kim

Hwang

et al. 2023

J Vet Clin

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The change in the position of the abdominal organs due to movement by respiration is one of the reasons behind inaccurate irradiation of organs during radiotherapy (RT). Although studies in human medicine have revealed on the respiratory movements of abdominal organs, there is little information and no reference data for dogs. The purpose of this study was to establish the reference values of abdominal organs movement in various postures using computed tomography (CT), and to compare the movements of organs between dorsal recumbency and ventral, right and left lateral recumbency during respiration. CT images for kidney, adrenal gland, medial iliac lymph node, urinary bladder, gallbladder, liver, stomach, and thoracic and lumbar vertebral body of five beagle dogs were acquired. The movements of organs were evaluated by comparing the end-expiratory and end-inspiratory images. Movements of the organs were evaluated by dividing it into right-to-left, dorsal-to-ventral, and cranial-to-caudal directions. The movements of abdominal organs according to the change in postures and respiration were establish. The movement of the bilateral organs was the least when the organs were in the downward position (p < 0.017). The movement of cranial-to-caudal direction was greater than the movement of the other directions in most of the organs. Data obtained in this study may be useful in selecting the appropriate posture that can reduce the movements of organs to be treated with RT, and the data could be useful for setting the planning target volume to consider the movements of the abdominal organs by respiration.

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“…Although there are a few reports on radiation therapy for large adrenal tumours with intravascular invasion (Dolera et al., 2016 , Maruo et al., 2019 ), surgery is considered to be the definitive treatment for canine adrenal PHEO (Lunn & Boston, 2020 ). Two case reports have described en bloc resection, including the CVC, for canine PHEO infiltrating the CVC (Louvet et al., 2005 , Guillaumot et al., 2012 ).…”

Section: Introductionmentioning

confidence: 99%

Preemptively planned en bloc resection of an extensive right adrenal pheochromocytoma involving the right hepatic division, caval thrombus and segmental caudal vena cava in a dog with Budd−Chiari‐like syndrome

Takeuchi

Ishigaki

Yoshida

et al. 2023

Veterinary Medicine & Sci

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Background: Surgical resection is the treatment of choice for canine adrenal pheochromocytomas (PHEOs). Information on en bloc resection of adrenal PHEO with tumour thrombus, right hepatic division and segmental caudal vena cava (CVC) running through the adrenal tumour and right hepatic division is limited.Objective: To describe the preemptively planned en bloc resection of an extensive right adrenal PHEO involving the right hepatic division, the caval thrombus and the segmental CVC in a dog with Budd−Chiari-like syndrome (BCLS). Methods:A 13-year-old castrated male miniature dachshund was referred for surgical treatment due to anorexia, lethargy and severe abdominal distension caused by abundant ascites. Preoperative computed tomography (CT) revealed a large mass in the right adrenal gland with a large caval thrombus obstructing the CVC and hepatic veins, which caused BCLS. Additionally, collateral vessels were formed between the CVC and azygos veins. No findings suggested obvious metastases. Based on CT findings, an en bloc resection of the adrenal tumour with caval thrombus, right hepatic division and segmental CVC was planned. Results:The preoperatively planned resection was feasible; the tumour was completely resected grossly. The operation time and total Pringle manoeuvre time were 162 min and 16 min 56 s, respectively. There was no postoperative hindlimb oedema, renal dysfunction, ascites or abdominal distention. The patient's clinical signs, including appetite, fully improved. Hospitalization lasted 16 days. However, the patient died on the 130th postoperative day due to suspected metastases and cachexia. Conclusions:Even in case of an extensive infiltration of adrenal PHEO causing BCLS, an en bloc resection might be successfully achieved based on the preoperative CT findings speculating the collateral vessels formed for caudal venous return.

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Conformal hypofractionated radiotherapy for dogs with large adrenal tumours

Cited by 3 publications

References 12 publications

Balloon catheter as an extraction device for caudal vena cava adrenal tumor thrombectomy in a dog: A case report

Balloon catheter as an extraction device for caudal vena cava adrenal tumor thrombectomy in a dog: A case report

Assessment of Abdominal Organs Movement by Respiration Using Computed Tomography in Dogs: A Pitfall for Radiation Therapy

Preemptively planned en bloc resection of an extensive right adrenal pheochromocytoma involving the right hepatic division, caval thrombus and segmental caudal vena cava in a dog with Budd−Chiari‐like syndrome

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