Congenital anomalies in the context of global surgery

Sitkin, Nicole; Farmer, Diana L.

doi:10.1053/j.sempedsurg.2015.09.004

Cited by 41 publications

(39 citation statements)

References 52 publications

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“…The provision of adequate surgical care to all children will, by preventing death or treating disability, allow more children to live up to their full potential. [12][13][14] Some of the leading causes of death of young people are treatable with surgery. One major cause of neonatal (first 28 days of life) death worldwide is congenital anomalies, many of which are treatable with surgery.…”

Section: Discussionmentioning

confidence: 99%

The Global Initiative for Children's Surgery: Optimal Resources for Improving Care

et al. 2017

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Section: Discussionmentioning

confidence: 99%

The Global Initiative for Children's Surgery: Optimal Resources for Improving Care

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“…Congenital anomalies represent epidemiological relevance because they result in mortality in $ 276,000 newborns per year worldwide. 10,11 Despite this, there are few studies that report the reality of the center-west region of Brazil.…”

Section: Discussionmentioning

confidence: 99%

“…21,23 It is known that 50% of the CAs may have an unknown etiology that can be attributed to genetic and environmental factors, including maternal nutritional aspects. 10,11 This etiological factor has become relevant due the drastic change in the demographics of pregnant women in the last decade, with a higher number of overweight or obese women at conception being observed. 26 In the present study, this phenomenon still cannot be observed, since the frequency of obese pregnant women was lower than the frequency of pregnant women of adequate weight.…”

Section: Discussionmentioning

confidence: 99%

“…Currently, 50% of the CAs have an unexplained etiology; however, some etiological factors have been reported, including genetic, nutritional, infectious, and/or environmental factors, among which maternal nutritional status is highlighted. 10,11 Despite this, there are few epidemiological studies on the prevalence of CAs and the association between the body mass index (BMI) of pregnant women and the development of CAs. [12][13][14] These studies include only overweight and obese pregnant women.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and Association of Congenital Anomalies According to the Maternal Body Mass Index: Cross-Sectional Study

Moraes

Mendonça

Melo

et al. 2019

Rev Bras Ginecol Obstet

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Objective To evaluate and compare the prevalence of structural congenital anomalies (CAs) according to maternal body mass index (BMI). Methods The present cross-sectional study involved pregnant women with fetuses diagnosed with structural CAs through morphological ultrasonography between November 2014 and January 2016. The nutritional status of the pregnant women was classified according to the gross value of the body mass index. The pregnant women were categorized into four groups: low weight, adequate weight, overweight, and obesity. Statistical analysis was performed using Stata/SE version 12.0 (Stata Corporation, College Station, TX), with values of p 0.05 considered statistically significant. Results A total of 223 pregnant women had fetuses diagnosed with CAs. The prevalence of structural CAs in pregnant women with low weight was of 20.18%, of 43.50% in pregnant women with adequate weight, of 22.87% in pregnant women with overweight, and of 13.45% in pregnant women with obesity. The prevalence of central nervous system (CNS) anomalies and of genitourinary system anomalies was high for the four groups of pregnant women. A positive association was observed between multiple anomalies in pregnant women with adequate weight (prevalence ratio [PR] ¼ 1.65; p 0.004) and between anomalies of the lymphatic system in obese pregnant women (PR ¼ 4.04, p 0.000). Conclusion The prevalence of CNS and genitourinary system anomalies was high in all of the BMI categories. Obese pregnancies were associated with lymphatic system anomalies. Therefore, screening and identification of the risk factors for CAs are important, regardless of the maternal BMI. Our findings reinforce the importance of discussing with pregnant women maternal nutrition and its effect on fetal development and on neonatal outcome.Carolina Leão de Moraes's ORCID is https://orcid.org/0000-0003-0755-0753.

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“…anomalies making up 9% of the surgical burden of disease worldwide, of which two-thirds may be avertable with surgical intervention [3,4]. Trauma, abdominal emergencies and tumors also contribute to the burden of surgical disease for patients of all ages [5,6].…”

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Global Initiative for Children’s Surgery: A Model of Global Collaboration to Advance the Surgical Care of Children

Surgery¹

2019

World j. surg.

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Background Recommendations by the Lancet Commission on Global Surgery regarding surgical care in low-and middle-income countries (LMICs) require development to address the needs of children. The Global Initiative for Children's Surgery (GICS) was founded in 2016 to identify solutions to problems in children's surgery by utilizing the expertise of practitioners from around the world. This report details this unique process and underlying principles. Methods Three global meetings convened providers of surgical services for children. Through working group meetings, participants reviewed the status of global children's surgery to develop priorities and identify necessary resources for implementation. Working groups were formed under LMIC leadership to address specific priorities. By creating networking opportunities, GICS has promoted the development of LMIC-LMIC and HIC-LMIC partnerships. Results GICS members identified priorities for children's surgical care within four pillars: infrastructure, service delivery, training and research. Guidelines for provision of care at every healthcare level based on these pillars were created. Seventeen subspecialty, LMIC chaired working groups developed the Optimal Resources for Children's Surgery (OReCS) document. The guidelines are stratified by subspecialty and level of health care: primary health center, first-, second-and third-level hospitals, and the national children's hospital. The OReCS document delineates the personnel, equipment, facilities, procedures, training, research and quality improvement components at all levels of care. Conclusion Worldwide collaboration with leadership by providers from LMICs holds the promise of improving children's surgical care. GICS will continue to evolve in order to achieve the vision of safe, affordable, timely surgical care for all children. Defining the need Surgical burden of disease Since the conclusion of the United Nations' Millennium Development Goals (MDGs) and through the ongoing work toward Sustainable Development Goals (SDGs), tremendous progress has been made toward reducing childhood mortality [1, 2]. However, the care of children with surgical diseases remains an underappreciated and underfunded area in health care, despite congenital Collaborating members are listed in the Acknowledgments.

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Congenital anomalies in the context of global surgery

Cited by 41 publications

References 52 publications

The Global Initiative for Children's Surgery: Optimal Resources for Improving Care

The Global Initiative for Children's Surgery: Optimal Resources for Improving Care

Prevalence and Association of Congenital Anomalies According to the Maternal Body Mass Index: Cross-Sectional Study

Global Initiative for Children’s Surgery: A Model of Global Collaboration to Advance the Surgical Care of Children

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