Congenital Blindness and Visual Impairment Cause Infection or Non Infection

Abstract

Conflict of interest: none declared.IntroductionAuthors are from reference documentation to archive at Organization of Federation of blind and visually impaired in central Serbia (Kragujevac), by retrograde analysis, of 2007-2012, comprehend two groups by etiology–clinical characteristics of congenital blindness and visually impaired, caused infection or non infection example.Aimto analyze relationship between infectious and non infectious of congenital blindness and visually impaired in our referent region and compare with world references.Material/methodsWith 6-years analysis included the most frequency cases of congenital blindness and visually impaired in two groups, according to presence or absence infectious causes. From infectious causes of congenital blindness and visually impaired are included: CMV – infection, congenital rubella syndrome, congenital toxoplasmosis, congenital syphilis and rare mixed syndrome. From non infectious causes are included: retinitis pigmentosa, retinopathy prematurity, primary congenital glaucoma, Leber’s congenital amaurosis and rare syndrome. Results: From total number of registered blind and visually impaired – 1308 (100%), over the last 6 years, the registration was 349 (26.68%) with congenital blindness and visually impaired. From recorder with the number of the most common congenital blindness and visually impaired–194 (55.59%) with infections cause, and 155 (44.41%) non infection cause. Conclusion: Congenital blindness has shown permanent increase in past 6 years, in group with infectious and with non infectious causes. Congenital blindness and visually impaired of the most common etiology among registered members of our association in Kragujevac is subject of our correlation and global trends mentioned observation of these diseases.

D-Xylose, a Stimulator of Heparan Sulfate Biosynthesis, Exhibits Antiviral Properties Against SARS-CoV-2, ZIKV, HCMV and HIV-1 NL4-3 In Vitro

“…However,, HCMV can have serious consequences for some people, such as individuals who have undergone transplantation, young adults who incurred a primary infection, immunocompromised people and especially young women who incurred a primary infection [1]. In the latter, the risk of virus transmission from mother to child is very high, and the consequences of this transmission are among the primary causes for congenital mental retardation [2], microcephaly [2], nongenetic hearing loss [3], vision loss [4] and nongenetic congenital malformations globally. Moreover, antiviral drugs developed for HCMV, such as valganciclovir and maribavir, are not recommended during pregnancy.…”