Congenital Iris Ectropion and Glaucoma Associated With Intestinal Neuronal Dysplasia: A Manifestation of a Neural Crest Syndrome

Grieshaber, Matthias C.; Orgül, Selim; Bruder, Elisabeth; Hadžiselimović, F.

doi:10.1001/archopht.124.10.1495

Cited by 7 publications

(6 citation statements)

References 10 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All 11 eyes required glaucoma surgery ( Table 1 ) to obtain IOP control with an average of 3.5 ± 2.1 surgeries per eye (median: 3, range: [1][2][3][4][5][6][7][8]. Time between glaucoma diagnosis and first glaucoma surgery was 1.2 ± 2.6 years (median: 0.01 years, range: 0.01-8.2 years) with no significant difference ( P = .1) between patients with unilateral (2.5 ± 3.6 years, range: 0-8.2 years) and bilateral (0.01 ± 0.01 years, range: 0-0.03 years) involvement.…”

Section: Resultsmentioning

confidence: 99%

Characteristics and Outcomes of Glaucoma Associated With Congenital Ectropion Uvea

Jacobson

Moroi

Bohnsack

2022

American Journal of Ophthalmology

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Characteristics and Outcomes of Glaucoma Associated With Congenital Ectropion Uvea

Jacobson

Moroi

Bohnsack

2022

American Journal of Ophthalmology

View full text Add to dashboard Cite

“…To date, there are approximately 50 cases of glaucoma secondary to congenital ectropion uvea reported in the English literature. 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 A review of these cases shows that glaucoma occurs in 80–90% of affected individuals. However, the age of glaucoma diagnosis ranges from birth to middle age (0–42 years) with the majority occurring between 3 and 15 years of age.…”

Section: Discussionmentioning

confidence: 99%

“…However, the age of glaucoma diagnosis ranges from birth to middle age (0–42 years) with the majority occurring between 3 and 15 years of age. 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 …”

Section: Discussionmentioning

confidence: 99%

“…Glaucoma is a common complication of congenital ectropion uvea and the age of diagnosis ranges from infancy to early adulthood. 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 The mechanisms underlying elevated intraocular pressures may be multi-factorial. Gonioscopy of younger children affected with congenital ectropion uvea shows open, but dysplastic angles with anterior insertion of the iris at the level of the trabecular meshwork.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Angle closure glaucoma in congenital ectropion uvea

Wang

Thuente²,

Bohnsack

2018

American Journal of Ophthalmology Case Reports

View full text Add to dashboard Cite

PurposeCongenital ectropion uvea is a rare anomaly, which is associated with open, but dysplastic iridocorneal angles that cause childhood glaucoma. Herein, we present 3 cases of angle-closure glaucoma in children with congenital ectropion uvea.ObservationsThree children were initially diagnosed with unilateral glaucoma secondary to congenital ectropion uvea at 7, 8 and 13 years of age. The three cases showed 360° of ectropion uvea and iris stromal atrophy in the affected eye. In one case, we have photographic documentation of progression to complete angle closure, which necessitated placement of a glaucoma drainage device 3 years after combined trabeculotomy and trabeculectomy. The 2 other cases, which presented as complete angle closure, also underwent glaucoma drainage device implantation. All three cases had early glaucoma drainage device encapsulation (within 4 months) and required additional surgery (cycloablation or trabeculectomy).Conclusions and importanceCongenital ectropion uvea can be associated with angle-closure glaucoma, and placement of glaucoma drainage devices in all 3 of our cases showed early failure due to plate encapsulation. Glaucoma in congenital ectropion uvea requires attention to angle configuration and often requires multiple surgeries to obtain intraocular pressure control.

show abstract

“…Congenital ectropion uvea is a rare ocular manifestation of neural crest syndrome [1]. It is a non-progressive anomaly characterized by presence of iris pigment epithelium on anterior surface of iris from the pigment ruff [2].…”

Section: Introductionmentioning

confidence: 99%

Bilateral Congenital Ectropion Uveae, Anterior Segment Dysgenesis and Aniridia with Microspherophakic Congenital Cataracts and RubeosisIridis

Pal¹,

Khan²,

Khan³

2018

JOCR

View full text Add to dashboard Cite

In recent times, multiple eye diseases have been seen associated with an increase in the rate of Demodex infestation as a possible cause, but in the particular case of dry eye syndrome in patients treated with platelet-rich plasma, this increase in mite may be relevant to guide a more adequate treatment focusing on the elimination of the mite in conjunction with the recovery of the ocular ecology. The demodex mite is a commensal parasite that lives in hair follicles, sebaceous glands and meibomian, which in a high rate of infestation can generate alterations in the ocular area. Performing an adequate diagnosis for the detection of the mite and treatment for its eradication can be effective for the recovery of the normal physiology of the tear film that constitutes a cause of dry eye.

show abstract

Congenital Iris Ectropion and Glaucoma Associated With Intestinal Neuronal Dysplasia: A Manifestation of a Neural Crest Syndrome

Cited by 7 publications

References 10 publications

Characteristics and Outcomes of Glaucoma Associated With Congenital Ectropion Uvea

Characteristics and Outcomes of Glaucoma Associated With Congenital Ectropion Uvea

Angle closure glaucoma in congenital ectropion uvea

Bilateral Congenital Ectropion Uveae, Anterior Segment Dysgenesis and Aniridia with Microspherophakic Congenital Cataracts and RubeosisIridis

Contact Info

Product

Resources

About