Congenital Renal Diseases

Renal dysplasia in a Boxer dog: case report

“…Definitive diagnosis of renal dysplasia should be performed based on the presence of characteristic lesions (Lees, 1996). Picut and Lewis (1987) proposed five criteria as primary renal dysplasia alterations in dogs.…”

“…In most cases, it is characterized by the presence of inadequate structures for the stage of development of the organism or the development of abnormal structures (Maxie, 1993;Lees, 1996). It is a common cause of renal insufficiency in dogs, being described in the following breeds: Lhasa Apso, Shih Tzu, Great Dane, Samoyed, Alaskan Malamute, King Charles Spaniel, Bulldog (Picut and Lewis, 1987), Labrador Retriever (Sarkiala et al, 1994), Rhodesian Ridgeback (Lobetti et al, 1996), Boxer and Finnish Harriers (Hoppe and Karlstam, 2000), Boxer, Rottweiler, Collie, and Irish Wolfhound (Peeters et al, 2000).…”

“…Some authors believe that the same occurs in Lhasa Apso dogs (O'Brien et al, 1982). There are evidences that this disease in Standard Poodle, Soft-coated Wheaten Terrier, Golden Retriever, Alaskan Malamut, and Chow Chow dogs has also a genetic origin (Lees, 1996).…”

“…The age of the diseased animals ranged from one month to 10 years (Picut and Lewis, 1987;Hoppe et al, 1990;Lees, 1996;Hoppe and Karlstam, 2000), but in general, the clinical evidences start being observed before the animal reaches the age of two years (Hoppe et al, 1990;Lees, 1996;Hoppe and Karlstam, 2000).…”

“…The animals may also present dehydration, anemia, oral ulcerations, and halitosis. A frequent outcome is the development of secondary hyperparathyroidism (Lazaretti et al, 2006) and renal lesion, which may originate skeletal deformations (fibrous osteodystrophy) that often affects the face bones most prominently (Lees, 1996).…”