Conhecimento Popular E Atividade Antimicrobiana De Matricaria Camomilla (Camomila), Psidium Guajava L.(goiabeira) E Pimpinela Anisum (Erva Doce)

Silva, Carina Assis Lima da; Santos, Caroline Mendes

doi:10.31792/21759766.viisic.2018.56

Cited by 1 publication

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“…Nevertheless, these compounds were applied as pesticides (De Oliveira et al, 2020;Lucio et al, 2019;Reges et al, 2019), but due to their structural constitution, they are being investigated for medical bioactivities, such as antibacterial (Silva, 2011), antifungal (David et al, 2018) and cytotoxic (Inácio, 2007).…”

Section: Introductionmentioning

confidence: 99%

In silico (Eco)toxicology and molecular docking of halogenated and oxygenated rotenoid derivatives

Sousa,

Belarmino,

Oliveira

et al. 2023

J. Eng. Exact Sci.

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The rotenoids are compounds widely disseminated in the agro-industrial and chemical-pharmacological sectors due to their structural constitution and versatility in biological activities, however, these present toxic activity for fish. Thus, the objective of this study is an in silico (eco)toxicological investigation of synthetic halogenated and oxygenated rotenoids with the use of aquatic bioindicators and molecular docking aiming to understand the biochemical behavior and environmental dynamics of these compounds. Therefore, it is inferred that the synthetic rotenoids denoted toxicological response at the chronic level made possible through physicochemical data and correlations between environmental dynamics, notwithstanding, the molecular coupling data corroborated with ecotoxicological assay enabling the rotenoids present bio-concentrative tendencies along the trophic chain causing deleterious effects in more developed organisms. Thus, the study is at an initial level, which enables new approaches in vitro and in vivo models for improvement and development of this study.

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