Conjugates of Bisphosphonates with Derivatives of Ursolic, Betulonic, and Betulinic Acids

Bekker, K. S.; Чуканов, Н. В.; Попов, С. А.; Григорьев, И. А.

doi:10.1007/s10600-013-0680-3

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Synthesis Of Building Blocks For Polymer Chemistry1

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Cited by 3 publications

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“…Studies of their photopolymerization indicated that they may be suitable for potential use in dentistry. Using DCC as a coupling agent, diethyl 1-(2-aminoethylamino)-1,1-ethylbisphosphonate was acylated by structurally variable natural acids, such as folic acid [140,141], ursulonic and betulinic acids [142], and trolox [141,143].…”

Section: Synthesis Of Building Blocks For Polymer Chemistrymentioning

confidence: 99%

Synthetic Procedures Leading towards Aminobisphosphonates

Chmielewska

Kafarski

2016

Molecules

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Abstract:Growing interest in the biological activity of aminobisphosphonates has stimulated the development of methods for their synthesis. Although several general procedures were previously elaborated to reach this goal, aminobisphosphonate chemistry is still developing quite substantially. Thus, innovative modifications of the existing commonly used reactions, as well as development of new procedures, are presented in this review, concentrating on recent achievements. Additionally, selected examples of aminobisphosphonate derivatization illustrate their usefulness for obtaining new diagnostic and therapeutic agents.

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