Presently, the coronavirus (COVID‐19) epidemic presents a major threat to global communal fitness also socio‐financial development. Ignoring worldwide isolation as well as shutdown attempts, the occurrence of COVID‐19 infected patients continues to be extremely large. Nonetheless, COVID‐19's final course, combined with the prevalence of emerging contaminants (antibiotics, pharmaceuticals, nanoplastics, pesticides, and so forth) in wastewater treatment plants (WWTPs), presents a major problem in wastewater situations. The research, therefore, intends near examine an interdisciplinary as well as technical greet to succor COVID‐19 with subsequent COVID cycles of an epidemic as a framework for wastewater treatment settings. This research investigated the potential for wastewater‐based epidemiology to detect SARS‐CoV‐2 also the enzymes happening in wastewater conditions. In addition, a chance for the incorporation into the WWTPs of emerging and robust technologies such as mesmeric nanobiotechnology, electrochemical oxidation, microscopy, and membrane processes to enhance the overall likelihood of environmental consequences of COVID‐19 also strengthen such quality of water is resolved.