Disasters can have wide-ranging effects on individuals and their communities. Loss of specific resources (e.g., household contents, job) following a disaster has not been well studied, despite the implications for preparedness efforts and post-disaster interventions. The present study used random-digit-dial methodology to recruit hurricane-affected adults from Galveston and Chambers, TX, counties one year after Hurricane Ike. Data from 1,249 survivors were analyzed to identify predictors of distress, including specific resource losses. Variables that were significantly associated with PTSD symptoms included sustained losses, hurricane exposure and socio-demographic characteristics; similar results were obtained for depressive symptoms. Together, these findings suggest risk factors that may be associated with the development of post-hurricane distress that can inform preparedness efforts and post-hurricane interventions.