Conservative Treatment of Female Stress Incontinence with Imipramine

Gilja, Ivan; Radej, M; Kovačić, Marijan; Parazajder, Josip

doi:10.1016/s0022-5347(17)49941-1

Cited by 66 publications

(22 citation statements)

References 17 publications

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“…Cardiotoxicity in the form of arrhythmias is also known to occur. A noncontrolled trial by Gilja et al [54] in 30 women with SUI treated with imipramine for 4 weeks showed subjective continence in 21 (71%). Lin et al [55] found that 60% of the patients treated with imipramine improved by more than 50% (based on pad weight).…”

Section: Imipraminementioning

confidence: 99%

Medical management of stress urinary incontinence: Is there a future?

Caruso¹,

Gomez²,

Gousse

2009

Curr Urol Rep

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Stress urinary incontinence (SUI) is a common problem among women worldwide. Multiple treatment modalities exist, ranging from physiotherapy to surgery. Numerous reports demonstrate mixed results for efficacy and safety of several oral agents used to treat SUI. Although there are data suggesting reasonable efficacy for several medications, surgery still remains the mainstay of treatment for most women. This article reviews the available oral agents that have been studied and assesses the data supporting their use while highlighting the limitations of each.

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Section: Imipraminementioning

confidence: 99%

Medical management of stress urinary incontinence: Is there a future?

Caruso¹,

Gomez²,

Gousse

2009

Curr Urol Rep

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“…These data show that estrogens do not appear to be an effective treatment for stress urinary incontinence. Although efficacy of imipramine has been suggested in open studies [69,70], no randomized clinical trial supports its clinical use. Propranolol, clenbuterol and methoxamine were reported to improve stress incontinence in studies with low level of evidence [71][72][73].…”

Section: Pharmacotherapymentioning

confidence: 99%

Dilemmas in the management of female stress incontinence: the role of pelvic floor muscle training

2006

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Treatment options for female stress urinary incontinence include pelvic floor muscle training, lifestyle interventions, bladder retraining, pharmacotherapy, anti-incontinence devices and surgery. Several consensus statements recommend pelvic floor muscle training as first line treatment. The aim of this review is to analyse all the currently available data and propose a treatment algorithm for clinical practice. A literature-based critical presentation of all treatment modalities, methods of assessing efficacy and comparison between them using a patient-centered approach was made. Many of the studies are observational, non-randomized with several methodological problems that lead to confusion. Emphasis was made to high quality randomized trials. The proposed treatment algorithm established only on evidence-based data. Management strategy however, must identify patient expectations and involve them in the decision-making more than traditional measures of treatment success.

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“…Son utilisation dans le traitement de l'IUE se justifie par une augmentation de la PCUM, qui passe de 34 à 48 mm Hg (p > 0,05) et par une amélioration subjective de la symptomatologie urinaire d'après l'étude de Gilja [16]. Son utilisation dans le traitement de l'IUE se justifie par une augmentation de la PCUM, qui passe de 34 à 48 mm Hg (p > 0,05) et par une amélioration subjective de la symptomatologie urinaire d'après l'étude de Gilja [16].…”

Section: L'imipramineunclassified