Considerations on the Ethiopathogenesis of Algae from the Primary Form of BMD

Coculescu, Bogdan Ioan; Manole, Gheorghe; Dinca, Valeriu-Gabi; Dinca, Alexandra-Ligia; Coculescu, Elena Claudia

doi:10.37358/rc.19.7.7354

Cited by 2 publications

(2 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If for the patients with diastolic ventricular dysfunction we analyse the four aforementioned parameters (EKG, electrocardiogram, serum dosage of hs-PCR and MPO) we believe a complex biomarker is formed, and its value lies in the fact that it increases the chances for having an early reliable diagnosis [17][18][19][20][21]. The medical literature highlights the importance of complex biomarkers which on one hand allow the stratification of risks and on the other hand point towards therapeutic opportunities as early as possible (table 1).…”

Section: Resultsmentioning

confidence: 99%

The Possible Serum Complex-Biomarkers for the Early Diagnosis of Diastolic Dysfunction with Preserved Systolic Function

Coculescu¹,

Manole²,

Dinca³

et al. 2019

Rev. Chim.

Self Cite

View full text Add to dashboard Cite

The present study looks at serum concentration levels of myeloperoxidase (MPO) and high-sensibility C Reactive Protein (hs-PCR) concentrations in 91 patients who presented thoracic pain localised on the sub-clavicular left side, which bothered them several times a day, where an episode lasted up to 30 minutes. Additional preclinical investigations revealed normal resting state/effort electrocardiograms, and the cardiac ultrasound revealed a diastolic cardiac dysfunction with a conserved ejection fraction. The conclusion of our study is that undertaking the exploratory tetrad (electrocardiogram, echocardiogram, serum dosage of MPO and hs-PCR) in patients who present anterior left pain, regardless of the degree of intensity, allows stratifying risks, at least through early detection of an existent diastolic cardiac dysfunction with conserved ejection fraction, which recommends changes in diet and lifestyle along with therapy.

show abstract

Section: Resultsmentioning

confidence: 99%

The Possible Serum Complex-Biomarkers for the Early Diagnosis of Diastolic Dysfunction with Preserved Systolic Function

Coculescu¹,

Manole²,

Dinca³

et al. 2019

Rev. Chim.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Burning Mouth Syndrome (BMS) is a chronic condition with controversial etiopathogenesis, the diagnosis of which requires a systematic, multidisciplinary medical approach and an attitude of exclusion of other oral conditions with similar clinical manifestations [1][2][3][4][5]. BMS manifests as chronic localized pain in the oral cavity.…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Burning Mouth Syndrome and Treatment for Thyroid Diseases

COCULESCU¹

2022

FARMACIA

Self Cite

View full text Add to dashboard Cite

The study aims to evaluate a possible association between the characteristics of pain symptoms and thyroid disorders with specific thyroid replacement medication. Our results indicate a statistically significant association between the presence of thyroid disorders and a change in pain intensity over time. Thus, in 42.86% of all patients with associated thyroid disorders, pain intensity increased over time. We also found a correlation between the increase in the frequency of dysgeusia and the increase in the intensity of the pain symptoms. The administration of drugs for thyroid disorders was significantly associated with the presence of dysgeusia. Also, analysing whether there is a significant correlation between the medication administered for thyroid disorders and the evolution of pain intensity over time, it was observed that in 51.72% of patients with thyroid medication, the pain intensity increased from the onset of the disease versus 20.51% of patients without thyroid medication in whom the intensity of the symptom increased. In conclusion, endocrine disorders and specific medications may be responsible for changes in the taste system. The increase in the frequency of dysgeusia is correlated with the increase in pain intensity in patients with thyroid disorders. RezumatScopul studiului a fost de a evalua o posibilă asociere între caracteristicile simptomatologiei algice și afecțiunile tiroidiene cu medicația substitutivă tiroidiană specifică. Rezultatele prelucrării statistice indică o asociere statistic semnificativă între prezența afecțiunilor tiroidiene și modificarea în timp a intensității algiei. Astfel, la 42,86% din totalul pacienților cu afecțiuni tiroidiene asociate, intensitatea algică s-a accentuat în timp. De asemenea, particulară studiului personal a fost constatarea existenței unei corelații între creșterea frecvenței disgeuziei și creșterea intensității simptomului algic. Administrarea de medicamente pentru afecțiuni tiroidiene este asociată statistic semnificativ cu prezența disgeuziei. De asemenea, analizând dacă există corelație semnificativ statistică între medicația administrată pentru afecțiunile tiroidiene și evoluția în timp a intensității algiei s-a observat că, la 51,72% din pacienții care prezintă medicație tiroidiană, intensitatea algiei a crescut de la debutul afecțiunii versus 20,51% din pacienții fără medicație tiroidiană la care s-a accentuat intensitatea simptomului. În concluzie, tulburările endocrine și medicația specifică pot fi responsabile de modificările sistemului gustativ, simptom frecvent prezent la acești pacienți. Creșterea frecvenței disgeuziei este corelată cu creșterea intensității durerii.

show abstract

Considerations on the Ethiopathogenesis of Algae from the Primary Form of BMD

Cited by 2 publications

References 11 publications

The Possible Serum Complex-Biomarkers for the Early Diagnosis of Diastolic Dysfunction with Preserved Systolic Function

The Possible Serum Complex-Biomarkers for the Early Diagnosis of Diastolic Dysfunction with Preserved Systolic Function

The Relationship Between Burning Mouth Syndrome and Treatment for Thyroid Diseases

Contact Info

Product

Resources

About