Constituents from the bark of Tabebuia impetiginosa

Nitric Oxide (NO) Production Inhibitory Constituents of Tabebuia avellanedae from Brazil

“…In this paper, we have reported two new iridoids (1, 2) and a new phenylethanoid glycoside (3), together with twelve known compounds (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). Compounds 1 and 2 have two methyl acetals in the molecule, which have possibility to be produced during the isolation.…”

“…The EtOAc-soluble fraction (IC 50 , 48.1 mg/ml), which showed stronger activity than the EtOAcinsoluble fraction (IC 50 , 54.5 mg/ml), was subjected to a series of chromatographic separation and preparative TLC to afford two new iridoids (1, 2) and a new phenylethanoid glycoside (3), together with twelve previously-reported compounds (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). The known compounds were identified by analysis of their spectroscopic data and comparison with literature data to be 2-(4- H-NMR spectra were also similar and revealed signals due to a tertiary methyls, three oxymethines, two aliphatic methylenes, two methoxyls, and two methylenes together with those of a p-substituted benzoyl group.…”

A new antifungal phenolic glycoside derivative, iridoids and lignans from Alibertia sessilis (vell.) k. schum. (Rubiaceae)

“…Others signals observed in 1 H and 13 C NMR spectra are consistent with glycosyl moieties. According to literature, 10 the comparison of the 13 C NMR data of the glycosidic moiety of various other analogous compounds, the structure of 1 seems to be composed of a glucosyl [δ C 103.2 (C-1′), 74.9 (C-2′), 77.9 (C-3′), 71.5 (C-4′), 76.9 (C-5′) and 68. and the syringoyl carbonyl group (δ C 167.9) indicated that the 3,5-dimethoxy-4-hydroxy-benzoyl group was attached to C-5′′ of the β-D-apiose. Finally, the proton at δ H 4.79 (H-1′ of glucose) was correlated with C-1 of the 3,4,5-trimethoxy phenyl group (δ C 155.9), indicating that the β-D-glucosyl moiety was located at C-1.…”

“…8 This paper reports the bioassay-guided isolation and structure elucidation of the new 3,4,5-trimethoxyphenyl-1- (Figure 1), and the known lignans (+)-lyoniresinol-3α-O-β-D-glucopyranoside (6), (-)-lyoniresinol-3α-O-β-D-glucopyranoside (7), which are being described for the first time for Rubiaceae. This paper also reports the isolation of iridoids geniposidic acid (2), geniposide (3), 6α-hydroxygeniposide (4) and 6β-hydroxygeniposide (5), phenolic acids, chlorogenic (8) and salicylic acid (9) and D-manitol (10). The antifungal activity of compound 1 against Cladosporium sphaerospermum and C. cladosporioides was detected by using direct bioautography.…”

Pau-D’arco-Roxo (Handroanthus impetiginosus (Mart. ex DC.) Mattos): Conhecimento e uso madeireiro em comunidades rurais do nordeste do Brasil

“…A árvore é utilizada na arborização urbana (Pestana, 2011), principalmente pela sua beleza, e também pelo seu potencial de sombreamento, que foi comprovado pela sua concentração de clorofila nas folhas e espectro de absorção de luz (Engel, 1991). A casca da H. impetiginosus é conhecida na medicina popular pela sua utilização no tratamento de diabetes, úlcera e sífilis (Warashina et al, 2006). Em virtude disso, grande parte dos estudos direcionados ao H. impetiginosus está relacionada aos seus potenciais antioxidante, antibiótico, bactericida, antifúngico e cicatrizante (Barbosa Filho, 2004;Antunes, 2006;Budni, 2007;Souza, 2008;Coelho et al, 2010).…”