Constituents of Crinoidea. 1. Isolation and Structure of Inositolphosphoceramide from the Feather Star Comanthus japonica.

Constituents of Crinoidea. 3. Isolation and Structure of a Glycosyl Inositolphosphoceramide-Type Ganglioside with Neuritogenic Activity from the Feather Star Comanthus japonica

“…On the other hand, the LCB was characterized as C 16 -sphingosine, based on GC-MS analysis of its TMS derivative. The stereochemistry of the ceramide moiety is presumed to be (2S, 3R, 4E), since the 1 H-NMR spectrum of the ceramide was in good agreement with that of the ceramide obtained from CJP1 7) which has the 2S, 3R, 4E configuration. Furthermore, signals due to the methyl groups are observed at 13.9 ppm in the 13 C-NMR spectrum of CJP4, which indicates that the LCB also has the normal type of alkyl chain.…”

“…[1][2][3][4][5][6] In the study of the GSLs of the feather star Comanthus japonica (Nipponumishida in Japanese), we reported on the isolation and structural elucidation of inositolphosphoceramide, CJP1, 7) and the glycosyl inositolphosphoceramide-type gangliosides CJP2 and CJP3. 8) Continuing the preceding studies, further isolation and characterization of the more polar ganglioside from C. japonica was conducted.…”

“…When CJP4 was hydrolyzed with 5% acetic acid, CJP1, L-myo-inositol-1-O-phosphoceramide, was obtained. In the previous papers, 7,8) CJP1 was described as D-myo-by misreading the value of the specific rotation of the reference compound. It is corrected to L-myo-in this paper.…”

Constituents of Crinoidea. 2. Isolation and Structure of the Novel Type Gangliosides from the Feather Star Comanthus japonica.

“…Structure of CJP2 In the negative ion FAB-MS spectrum, CJP2 showed quasi-molecular ion peaks due to (MϪH) Ϫ at m/z 1155 and 1183 together with fragment ion peaks similar to those of CJP1 2) as shown in Fig. 1.…”

Constituents of Crinoidea. 5. Isolation and Structure of a New Glycosyl Inositolphosphoceramide-Type Ganglioside from the Feather Star Comanthina schlegeli

“…[1][2][3] In the study of the GSLs of the crinoidea, we reported on the isolation and structural elucidation of cerebrosides, 4) inositolphosphoceramide, 5) and the glycosyl inositolphosphoceramide-type gangliosides 6,7) from the feather star Comanthus japonica. Continuing the preceding studies, isolation and characterization of GSLs from the feather star Comanthina schlegeli (Hanaumishida in Japanese) was conducted.…”