Construction and evaluation of a flow injection micro-analyser based on urethane–acrylate resin

Fonseca, Alexandre; Raimundo, Ivo M.; Rohwedder, Jarbas José R.; Ferreira, Luiz Otávio

doi:10.1016/j.aca.2007.09.051

Cited by 31 publications

(18 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…51,61,65 Flow analysis has been pointed out as a powerful tool for green analytical chemistry. 66 Minimization of reagent consumption and waste generation is inherent to the process, but it is more evident in micro-flow analyzers, 19,51 as well as in some approaches such as merging zones, 7 SIA, 57 multicommutation, 11 and multipumping. 42 Moreover, ingenious approaches such as exploitation of hanging drops, 67 reuse of chemicals (e.g., an immobilized reagent used for reversible analyte sorption) 35 and even reagentless procedures are feasible.…”

Section: Looking Forward: Research Perspectives On Flow Analysismentioning

confidence: 99%

“…19 Moreover, novel approaches are feasible because of the typical dispersion pattern and the large surface-to-volume ratios inherent to microchannels. In this sense, several approaches have been exploited to build up micro-flow analyzers.…”

Section: Looking Forward: Research Perspectives On Flow Analysismentioning

confidence: 99%

“…In this sense, several approaches have been exploited to build up micro-flow analyzers. 19,20,62,63 A recent proposal refers to chip-based manifolds obtained with 3D printers, which can also integrate the flow cell. An example of application is the catalytic fluorimetric determination of iodide in seawater, achieving a detection limit of 300 ng L -1 .…”

Section: Looking Forward: Research Perspectives On Flow Analysismentioning

confidence: 99%

“…6 The innovations encompassed novel flow approaches (e.g., merging zones, 7 zone trapping, 8 zone sampling, 9 monosegmented flow analysis, 10 multicommutation, 11 and flow-batch analysis), 12 as well as the pioneering coupling to different detection techniques (e.g., flame atomic absorption spectrometry (FAAS), 13 inductively coupled plasma optical emission spectrometry (ICP OES), 14 turbidimetry 15 and enthalpimetry) 16 and processes (e.g., ion-exchange 17 and liquid-liquid extraction). 18 More recent advances include new alternatives for miniaturization (micro-FIA 19 and micro-flow batch analyzers), 20 exploitation of detection by digital images, 21 as well as stepwise elution in sequential injection chromatography. 22 This work is a critical overview of the main contributions of flow analysis to modern analytical chemistry, also highlighting the current status of this research field based on a literature survey.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Flow Analysis: Looking Back and Forward

Rocha¹

2018

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

Flow analysis changed significantly the way of performing chemical analysis by (i) mechanization of analytical procedures in a continuous flowing stream with minimal sample intercontamination; (ii) analytical measurements without attaining chemical equilibria, thus increasing the applicability of kinetic methods and allowing the exploitation of non-quantitative processes; (iii) exploitation of concentration gradients and (iv) use of unstable reagents or measurement of unstable products. Flow-based procedures are generally characterized by high sample throughput, improved precision, minimized waste generation, and often better selectivity. The performance of detection systems is usually improved because of the in-line sample conditioning and measurements under reproductive dynamic conditions and timing. However, after achieving several innovations, perspectives for further developments have been questioned mainly because of the recent decrease in the number of publications on flow analysis. The aim of this review is then to discuss the impact of flow-based methods on chemical analysis, emphasizing recent applications and developments, including miniaturization, bioanalysis, microextractions, green analytical chemistry and synergic hyphenation with other techniques and processes. The author's personal view about research perspectives in the field is also presented.

show abstract

Section: Looking Forward: Research Perspectives On Flow Analysismentioning

confidence: 99%

Section: Looking Forward: Research Perspectives On Flow Analysismentioning

confidence: 99%

Section: Looking Forward: Research Perspectives On Flow Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Flow Analysis: Looking Back and Forward

Rocha¹

2018

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

show abstract

“…For this reason, simpler, cheaper and faster technologies have been developed to promote the rapid spread of miniaturized analytical systems worldwide. [10][11][12] Among the alternative fabrication methodologies, tonerbased techniques offer simplicity and low instrumental requirements, thus making possible their implementation in any laboratory or research center. 13,14 Toner was firstly explored for microfabrication in 2001, when Tan et al 15 suggested the use of a photocopying machine to create a high-relief master for prototyping of microfluidic devices in poly(dimetilsyloxane) (PDMS) substrate.…”

Section: Introductionmentioning

confidence: 99%

Colorimetric Detection of Glucose in Biological Fluids Using Toner-Based Microzone Plates

Silva

Oliveira

Coltro

2016

Journal of the Brazilian Chemical Society

View full text Add to dashboard Cite

This report describes the use of toner-based microzone plates for quantitative determination of glucose in artificial urine and human serum samples using colorimetric detection. The proposed approach has exhibited a linear response for glucose concentration levels from 0 to 10 mmol L , respectively. The glucose analysis in artificial serum samples revealed error lower than 5% in comparison with certified values provided by the supplier. Lastly, the proposed approach has also provided suitable accuracy (92-105%) for glucose measurements in artificial urine samples. Keywords: bioanalytic, clinical assay, disposable device, point-of-care testing, portable instrumentation IntroductionIn the last years, the miniaturization of analytical systems has received considerable attention due to their attractive advantages including low reagent and sample consumption, portability, minimal waste generation, short time analysis, and high-throughput capability. [1][2][3][4][5][6][7] Standard photolithography is one of the main microfabrication technologies allowing the fabrication of microfluidic channels on different platforms including glass, silicon and quartz. Although this technology provides excellent resolution, it is laborious, expensive and time consuming. 8,9 Furthermore, cleanroom facilities and sophisticated instrumentation are required thereby limiting the access to few research groups. For this reason, simpler, cheaper and faster technologies have been developed to promote the rapid spread of miniaturized analytical systems worldwide. [10][11][12] Among the alternative fabrication methodologies, tonerbased techniques offer simplicity and low instrumental requirements, thus making possible their implementation in any laboratory or research center. 13,14 Toner was firstly explored for microfabrication in 2001, when Tan et al. 15 suggested the use of a photocopying machine to create a high-relief master for prototyping of microfluidic devices in poly(dimetilsyloxane) (PDMS) substrate. In 2003, do Lago et al. 16 proposed the direct fabrication of microfluidic devices using a laser printer for the deposition of toner layers on polyester films followed by a thermal lamination for sealing of channels at low temperature. Since this pioneering report, laser printing technology (LPT) has been used to produce microfluidic toner-based analytical devices (µTADs) at very low cost. Due to the advantages associated with the fabrication simplicity and low cost per device, some authors have extended the use of LPT to produce toner-based devices for clinical assays involving the use of portable equipment like cell phone camera, scanner, digital camera and handheld optical microscope for colorimetric measurements. The association of toner-based devices and colorimetric Colorimetric Detection of Glucose in Biological Fluids Using Toner-Based Microzone Plates J. Braz. Chem. Soc. 198 detection is quite attractive for point-of-care (POC) testing due to operational simplicity and low instrumental requirements. Furthermore, the ment...

show abstract

Strategies to Make Methods Based on Flow Injection Analysis Greener

Bezerra

Santelli

Lemos

et al. 2020

CLEAN Soil Air Water

View full text Add to dashboard Cite

The implementation of flow injection analysis (FIA) systems and correlated techniques in the laboratory routine provides an increase of analytical throughput and the reduction of risks of analyte losses and contamination. Naturally, it contributes to the reduction of reagent consumption and minimization of waste generation. This paper presents and discusses an overview of the main strategies adopted to make methods based on FIA systems more environmentally friendly, and offers a review of these methods that covers the period from January 2002 to December 2019. Strategies based on reagent management (adoption of procedures without reagents, replacement of toxic reagents, recycling and reuse of reagents and, use of immobilized reagents), the online waste treatment, and the improvements of FIA systems (flow system configurations that avoid reagent wastage, use of green detectors, automation, and miniaturization) are approached in this perspective.

show abstract

Construction and evaluation of a flow injection micro-analyser based on urethane–acrylate resin

Cited by 31 publications

References 17 publications

Flow Analysis: Looking Back and Forward

Flow Analysis: Looking Back and Forward

Colorimetric Detection of Glucose in Biological Fluids Using Toner-Based Microzone Plates

Strategies to Make Methods Based on Flow Injection Analysis Greener

Contact Info

Product

Resources

About