Introduction: This first-time novel pilot study explored RN-BS students’ perceived effectiveness of utilizing vSim for Nursing® as a clinical replacement with a second aim that explored the efficacy of their preparation.Methods: Outcomes of this quantitative study explored the effectiveness of vSim for Nursing utilized the Simulation Effectiveness Tool – Modified (SET-M).Results: Frequency distributions demonstrated majority (n = 14) strongly agreed on the effectiveness of vSim for learning, with all items ranging from 50% (n = 7) to 78.6% (n = 11). Debriefing had the overall highest responses, 57.1% (n = 8) to 78.6% (n = 11). Majority strongly agreed that their preparation was highly effective, 71.43% (n = 10) to 85.71% (n = 12).Conclusions: vSim for Nursing was perceived to be an efficacious clinical practice replacement tool while feeling prepared to achieve the learning outcomes was beneficial. Debriefing continues to be a crucial and fundamental facet to any mode of simulation. Virtual simulation experiences can bridge the gap to assist students to further their knowledge and confidence.